ReviewBMC oral health2025
Association between periodontal disease and age-related cognitive impairment: a narrative review.
Review in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Salivary protein macromolecules as diagnostic and therapeutic biomarkers linking oral health and neurodegenerative diseases-emerging mechanisms and future perspectives.Inflammopharmacology · 2026Review
- Article
- Clinical practice guidelines and consensus statements integrating periodontal disease into cardiology, diabetes care and dementia: A scoping review and gap analysis.Medicina oral, patologia oral y cirugia bucal · 2026Article
- A Network Analysis of Food Intake and Cognitive Function in Older Adults with Multimorbidity: A National Cross-Sectional Study.Nutrients · 2025Article
- Accelerated biological aging mediates the association between periodontal disease and cognitive function in older adults.Innovation in aging · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundPrevious studies have shown associations between periodontal disease and age-related cognitive impairment. However, little is known about the different cognitive functions that may be affected in patients with periodontal disease.
methodsWe reviewed the recent literature to better understand the bidirectional relationship between cognitive function and periodontal disease, and to explore the cognitive assessments that may be useful when investigating this relationship. We also reviewed the literature around improving periodontal health in older adults presenting with cognitive impairment, which may improve their cognition.
resultsThere is a bidirectional relationship between periodontal disease and cognitive impairment. We also found that visuospatial function, attention, memory, and language are important cognitive domains that may be impaired in older people with periodontal disease, possibly because these factors are associated with the ability to adequately brush one's teeth. Furthermore, we noted that the choice of cognitive assessment may be particularly important when studying cognitive function in relation to periodontal health. To improve periodontal health in older people with cognitive impairment, partner-assisted interventions, adequate toothbrushing, and the use of a powered toothbrush have all been proposed. The early initiation of regular oral care visits, education for individuals, improving cooking skills, and dietary/caloric restrictions may also contribute to improving periodontal health.
conclusionsThe bidirectional nature of the relationship between periodontal health and cognitive function is important for older adults presenting with cognitive impairment. Furthermore, improvements in periodontal health may help to improve cognitive impairment. The appropriate assessment of cognitive function will contribute to preserving and improving oral health in older people with periodontal disease.
Indexed as
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.