Evidence map›Paper›PMID 40082953›Full record

ArticlePorcine health management2025

A novel intradermal combination vaccine for PCV2 and Mycoplasma hyopneumoniae protection in swine: its use with Lawsonia intracellularis and PRRSV vaccines.

Basav N Hangalapura, Maarten Witvliet, Antonius A C Jacobs, Ruud P A M Segers

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Porcine health management, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Basav N HangalapuraMSD Animal Health, PO Box 31, Boxmeer, 5830 AA, The Netherlands. Basav.Nagaraj@merck.com.
Maarten WitvlietMSD Animal Health, PO Box 31, Boxmeer, 5830 AA, The Netherlands.
Antonius A C JacobsMSD Animal Health, PO Box 31, Boxmeer, 5830 AA, The Netherlands.
Ruud P A M SegersMSD Animal Health, PO Box 31, Boxmeer, 5830 AA, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The combined, intradermal application of multiple vaccines against key diseases in swine offers many benefits, including reduced time and labor costs, and improved animal welfare due to fewer injections and manipulations. This study investigated the efficacy of a newly developed intradermal combination vaccine for Porcine circovirus 2 (PCV2) and Mycoplasma hyopneumoniae (M hyo) (PCV M Hyo ID vaccine) in swine. The vaccine was evaluated for its efficacy against PCV2 and M hyo infection and its concurrent mixed use with Lawsonia intracellularis (LI) and non-mixed use with Porcine reproductive and respiratory syndrome virus (PRRSV) vaccines. The findings demonstrated that the PCV M Hyo ID combination vaccine is efficacious against PCV2 and M hyo infection. Furthermore, the new PCV M Hyo ID combination vaccine can also be administered simultaneously and at the same anatomical location after mixing with LI ID vaccine, and next to PRRS ID vaccine, to efficiently protect pigs from all four major diseases in swine. The efficacy with the combination of vaccines was equivalent to that of the single vaccines.

Indexed as

Combination vaccineIntradermal vaccinationLawsonia intracellularisPorcilis® PCV M Hyo ID vaccinePorcine reproductive and respiratory syndromeSwine vaccines

Identifiers

PMID40082953
PMCPMC11905488

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.