Evidence map›Paper›PMID 40084366›Full record

ArticleAmerican journal of cancer research2025

Association of concomitant MASLD and hepatitis B virus with clinical prognosis in hepatocellular carcinoma after curative resection.

Chih-Jan Ko, Hung-Yu Lin, Pei-Min Hsieh, Wen-Lung Wang, Szu-Ying Chen, Li-Wei Chou, Yaw-Sen Chen, Yu-Wei Huang, Wen-Chao Ho, Chih-Wen Lin

Abstract read
In one paragraph

Article in American journal of cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chih-Jan KoDepartment of Public Health, China Medical University Taichung, Taiwan.
Hung-Yu LinDepartment of Surgery, E-Da Cancer Hospital, I-Shou University Kaohsiung, Taiwan.
Pei-Min HsiehDepartment of Surgery, E-Da Dachang Hospital, I-Shou University Kaohsiung, Taiwan.
Wen-Lung WangDivision of Gastroenterology and Hepatology, Department of Medicine, E-Da Hospital, I-Shou University Kaohsiung, Taiwan.
Szu-Ying ChenSchool of Medicine, College of Medicine, I-Shou University Kaohsiung, Taiwan.
Li-Wei ChouDepartment of Physical Medicine and Rehabilitation, China Medical University Hospital Taichung, Taiwan.
Yaw-Sen ChenDepartment of Surgery, E-Da Hospital, I-Shou University Kaohsiung, Taiwan.
Yu-Wei HuangSchool of Medicine, College of Medicine, I-Shou University Kaohsiung, Taiwan.
Wen-Chao HoDepartment of Public Health, China Medical University Taichung, Taiwan.
Chih-Wen LinDivision of Gastroenterology and Hepatology, Department of Medicine, E-Da Hospital, I-Shou University Kaohsiung, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The term "metabolic dysfunction-associated steatotic liver disease" (MASLD) was introduced to replace the term "nonalcoholic fatty liver disease". The prevalence of MASLD is increasing worldwide. The prevalence of concomitant MASLD and hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) is also increasing. This study explored the effect of the coexistence of MASLD and HBV on clinicopathological features and long-term clinical prognoses in patients with MASLD-related and/or HBV-related HCC after curative hepatectomy. The study retrospectively collected the data of 653 patients with HCC who had undergone curative hepatectomy between 2011 and 2022. We assessed the association of histologically confirmed MASLD with HCC recurrence and mortality. Of 653 patients, 320 (49.0%), 103 (15.8%), and 230 (35.2%) had concomitant MASLD and HBV, MASLD only, and HBV only, respectively. The median follow-up period was 5.1 years. Patients with concomitant MASLD and HBV were at a significantly increased risk of HCC recurrence (

Indexed as

hepatitis B virushepatocellular carcinomaMetabolic dysfunction-associated steatotic liver diseasemortalityrecurrence

Identifiers

PMID40084366
PMCPMC11897618

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.