Evidence map›Paper›PMID 40087166›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Alpha-1 antitrypsin deficiency and risk of sleep apnea: a nationwide cohort study.

Lucas Møller Larsen, Sine Voss Winther, Asbjørn Kørvel-Hanquist, Sarah C W Marott, Eskild M Landt, Preben Homøe, Børge G Nordestgaard, Morten Dahl

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Alpha1-Antitrypsin in Lung Diseases: A Cross-Sectional Observational Study.International journal of molecular sciences · 2025
    Observational
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lucas Møller LarsenDepartment of Clinical Biochemistry, Zealand University Hospital, 4600, Køge, Denmark.
Sine Voss WintherDepartment of Clinical Biochemistry, Zealand University Hospital, 4600, Køge, Denmark. sivw@regionsjaelland.dk.
Asbjørn Kørvel-HanquistDepartment of Otorhinolaryngology and Maxillofacial Surgery, Zealand University Hospital, Køge, Denmark.
Sarah C W MarottDepartment of Clinical Biochemistry, Zealand University Hospital, 4600, Køge, Denmark.
Eskild M LandtDepartment of Clinical Biochemistry, Zealand University Hospital, 4600, Køge, Denmark.
Preben HomøeDepartment of Otorhinolaryngology and Maxillofacial Surgery, Zealand University Hospital, Køge, Denmark.
Børge G NordestgaardDepartment of Clinical Biochemistry, Herlev-Gentofte University Hospital, Herlev, Denmark.
Morten DahlDepartment of Clinical Biochemistry, Zealand University Hospital, 4600, Køge, Denmark.

Funding

Alpha-1 Foundation 612336Novo Nordisk Fonden NNF19OC0058811Region Sjælland R19A341B233
6 · The paper itself

Abstract

objectivesα

methodsWe tested this hypothesis by doing a nationwide cohort study of 2702 individuals diagnosed with α

resultsIndividuals with α

conclusionIndividuals with α

Indexed as

alpha 1-Antitrypsin DeficiencySleep Apnea, ObstructiveSleep Apnea SyndromesAdolescentAdultAgedChildCohort StudiesFemaleHumansMaleMiddle AgedRisk FactorsComorbiditiesEpidemiologyGeneticsObstructive sleep apneaSleep disorder

Identifiers

PMID40087166
PMCPMC12055952

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.