Evidence map›Paper›PMID 40087244›Full record

ArticleObesity surgery2025

Reflux-Related Abnormalities at Distal oesophagus, Gastric Pouch and Anastomotic Site 4 Years After OAGB: Diagnostic Accuracies of Endoscopy Compared to Biopsy and of Symptoms Compared to Both.

Mohamad Hayssam ElFawal, Osama Taha, Mahmoud Abdelaal, Dyaa Mohamad, Ihab I El Haj, Hani Tamim, Karim ElFawal, Walid El Ansari

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Mohamad Hayssam ElFawalDepartment of Surgery, Beirut Arab University, Beirut, Lebanon.
Osama TahaBariatric Unit, Plastic Surgery Department, Assiut University, Assiut, Egypt.
Mahmoud AbdelaalBariatric Unit, Plastic Surgery Department, Assiut University, Assiut, Egypt.
Dyaa MohamadDepartment of Surgery, American Academy of Cosmetic Surgery Hospital, Dubai, United Arab Emirates.
Ihab I El HajDepartment of Gastroenterology, Faculty of Medicine, University of Saint Georges, Beirut, Lebanon.
Hani TamimDepartment of Biostatistics, American University of Beirut, Beirut, Lebanon.
Karim ElFawalMount Lebanon Hospital, University of Balamand, Beirut, Lebanon.
Walid El AnsariCollege of Medicine, Ajman University, Ajman, United Arab Emirates. w.elansari@ajman.ac.ae.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of the current study is to appraise the diagnostic accuracy of upper endoscopy (UE) vs histopathological assessment of patients after one-anastomosis gastric bypass (OAGB), and the presence/absence of symptoms vs these two diagnostic modalities.

methodsRetrospective study of 50 consecutive patients who underwent OAGB during April 2019-April 2020 and consented to participate. Symptoms (symptoms score questionnaire), macroscopic and microscopic data were collected 4 years later to assess distal oesophageal, gastric pouch and anastomotic site changes. Diagnostic accuracies (sensitivity, specificity, positive/negative predictive values) of UE vs biopsy and symptoms vs both were assessed.

resultsMean age was 48.6 ± 13.3 years; 66% were females. At 4 years, 54% had symptoms (symptom score ≥ 4). There were no dysplasia or cancer among this series. UE abnormalities included non-erosive gastritis (44%) and ulcer/s or erosive gastritis (16% each); histopathology abnormalities included chronic gastritis (80%) and Barrett's oesophagus (14%). For UE compared to biopsy, highest sensitivity (76.5%) was at the level of distal oesophagus and highest specificity (100%) at anastomotic site. Pertaining to symptoms compared to investigative modality, highest sensitivity (81.5%) was in relation to symptoms vs UE, while highest specificity (82.6%) was for symptoms vs biopsy.

conclusionsIt is generally not recommended that (a) UE be used to forecast biopsy abnormalities or lack thereof, except at the anastomotic site, and (b) symptoms or lack thereof be used to forecast the findings of investigative modalities, except with caution, to forecast UE findings in identifying healthy individuals, or to forecast biopsy findings in identifying diseased individuals. Long-term routine follow-up is needed post-OAGB regardless of whether patients are symptomatic or otherwise to rule in or out possible macroscopic/microscopic pathologies. Further research on UE and biopsy findings post-OAGB and their relationships with each other and with symptoms/lack thereof are required to strengthen the thin evidence base.

Indexed as

EsophagusGastric BypassGastroesophageal RefluxObesity, MorbidPostoperative ComplicationsAdultAnastomosis, SurgicalBarrett EsophagusBiopsyEsophagoscopyFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesBariatric surgeryBile refluxEndoscopyGastric bypassObesity

Identifiers

PMID40087244

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.