Evidence map›Paper›PMID 40087261›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025

Periodic discharges in portable EEG of critically ill patients with altered mentation; an alerting and alarming phenomena with helpful clues.

Azra Zafar, Danah Aljaafari, Erum Shariff, Rizwana Shahid, Norah A Alkhaldi, Saima Nazish, Mohammed Alshurem, Abdullah Saleh AlAmri, Foziah Jabbar Gossab AlShamrani

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Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Azra ZafarDepartment of Neurology, College of Medicine, King Fahd University Hospital, Imam Abdulrahman Bin Faisal University, Dammam, 34212, Kingdom of Saudi Arabia. azafar@iau.edu.sa.ORCID http://orcid.org/0000-0001-6027-7229
Danah AljaafariDepartment of Neurology, College of Medicine, King Fahd University Hospital, Imam Abdulrahman Bin Faisal University, Dammam, 34212, Kingdom of Saudi Arabia.
Erum ShariffDepartment of Neurology, College of Medicine, King Fahd University Hospital, Imam Abdulrahman Bin Faisal University, Dammam, 34212, Kingdom of Saudi Arabia.
Rizwana ShahidDepartment of Neurology, College of Medicine, King Fahd University Hospital, Imam Abdulrahman Bin Faisal University, Dammam, 34212, Kingdom of Saudi Arabia.
Norah A AlkhaldiDepartment of Neurology, College of Medicine, King Fahd University Hospital, Imam Abdulrahman Bin Faisal University, Dammam, 34212, Kingdom of Saudi Arabia.
Saima NazishDepartment of Neurology, College of Medicine, King Fahd University Hospital, Imam Abdulrahman Bin Faisal University, Dammam, 34212, Kingdom of Saudi Arabia.
Mohammed AlshuremDepartment of Neurology, College of Medicine, King Fahd University Hospital, Imam Abdulrahman Bin Faisal University, Dammam, 34212, Kingdom of Saudi Arabia.
Abdullah Saleh AlAmriDepartment of Neurology, College of Medicine, King Fahd University Hospital, Imam Abdulrahman Bin Faisal University, Dammam, 34212, Kingdom of Saudi Arabia.ORCID http://orcid.org/0000-0002-0642-3587
Foziah Jabbar Gossab AlShamraniDepartment of Neurology, College of Medicine, King Fahd University Hospital, Imam Abdulrahman Bin Faisal University, Dammam, 34212, Kingdom of Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPeriodic discharges (PDs) in critically ill patients with altered mental status (CIPAMS) have important implications. This study aimed to describe different characteristics of PDs in CIPAMS using routine electroencephalogram.

methodsThis retrospective study was carried out at King Fahd University Hospital. The EEG recordings of CIPAMS reporting PDs were reviewed. All patients had at least 30 min of portable EEG recording (pEEG). Patients were dichotomized into two groups according to PDs. Clinical and radiological variables between the two groups were compared using Chi-square tests and Odds ratio. P value < 0.05 was considered statistically significant.

resultsThe electronic charts of 295 consecutive CIPAMS were reviewed. PDs, detected in 21% of the patients, were significantly more frequent in women as compared to men (OR = 1.71,CI = 1.09-2.67,P = 0.01). The mean (SD) age of the patients was significantly higher in the group having PDs than without (P = 0.01). LPDs were detected in 41, and GPDs in 17 patients. Chronic neurological illness, encephalitis, and brain tumor had a significant association with LPDs, whereas metabolic derangement and Creutzfeldt-Jakob disease with GPDs. The frequency and peri-ictal features were important determinants of non-convulsive seizure (NCS). Overall, PDs were associated with an increased likelihood of unfavorable outcomes and mortality.

Indexed as

Critical IllnessElectroencephalographyAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesCritical illnessElectroencephalogramElectrographic seizurePeriodic discharges

Identifiers

PMID40087261

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.