Evidence map›Paper›PMID 40087564›Full record

ArticleGenes & nutrition2025

Use of Nigella sativa silver nanocomposite as an alternative therapy against thioacetamide nephrotoxicity.

Fatma M El-Demerdash, Ansam B Al Mhanna, Raghda A El-Sayed, Tarek M Mohamed, Maha M Salem

Abstract read
In one paragraph

Article in Genes & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fatma M El-DemerdashDepartment of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, Alexandria, 21526, Egypt. eldemerdashf@alexu.edu.eg.ORCID http://orcid.org/0000-0001-5624-9145
Ansam B Al MhannaDepartment of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, Alexandria, 21526, Egypt.
Raghda A El-SayedDepartment of Environmental Studies, Institute of Graduate Studies and Research, Alexandria University, Alexandria, 21526, Egypt.
Tarek M MohamedBiochemistry Division, Department of Chemistry, Tanta University, Tanta, 31527, Egypt.
Maha M SalemBiochemistry Division, Department of Chemistry, Tanta University, Tanta, 31527, Egypt.ORCID https://orcid.org/0000-0002-9108-6932

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nigella sativa (N. sativa) L. (Ranunculaceae), commonly referred to as black cumin, has a long history of usage as an herbal remedy. It has been utilized conventionally and in clinical settings to treat various illnesses. Six groups of male Wister rats were randomly selected as Gp I, represented as control; Gp II administered N. sativa aqueous extract (NSAE); 200 mg/kg/d, Gp III received N. sativa silver nanocomposite (NS-Ag-NC); 0.25 mg/kg/d; Gp IV administered thioacetamide (TAA);100 mg/kg; thrice weekly and Gps V and VI administered NSAE and NS-Ag-NC with TAA for six weeks, respectively. Findings showed that GC-MS analysis of NSAE has a high concentration of phytochemicals with strong antioxidant activity. Results revealed that TAA administration elevated TBARS, H

Indexed as

Kidney injuryN. sativa aqueous extract GC-MS analysisN. sativa-silver nanocompositeOxidative stressThioacetamide

Identifiers

PMID40087564
PMCPMC11909921

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.