Evidence map›Paper›PMID 40088135›Full record

ArticleWorld journal of surgery2025

Patients With Severe Obesity Are Made Eligible for Complex Abdominal Wall Repair After Preoptimization With GLP-1 Agonists: Results of a Bicentric Pilot Study.

Benoit Romain, Vincent Pfirsch, Simone Manfredelli, Thomas Leroi, Fadi Salman, Ouidad Sami, Diane Westerfeld-Ruillier, Séverine Ledoux, David Moszkowicz

Abstract readMulticenter Study
In one paragraph

Article in World journal of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Benoit RomainService de Chirurgie Générale et Digestive, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.ORCID 0000-0002-8315-1079
Vincent PfirschService de Chirurgie Générale et Digestive, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Simone ManfredelliService de Chirurgie Générale et Digestive, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Thomas LeroiEtablissement SMR des Trois-Epis, Trois Epis, France.
Fadi SalmanService de Chirurgie Digestive, AP-HP, Hôpital Louis Mourier, DMU ESPRIT-GHU AP-HP, Nord-Université Paris Cité, Colombes, France.
Ouidad SamiExplorations fonctionnelles, Centre Intégré Nord Francilien de l'Obésité, AP-HP.Nord - Université Paris Cité, Colombes, France.
Diane Westerfeld-RuillierUGECAM Alsace, Illkirch-Graffenstaden, France.
Séverine LedouxExplorations fonctionnelles, Centre Intégré Nord Francilien de l'Obésité, AP-HP.Nord - Université Paris Cité, Colombes, France.
David MoszkowiczService de Chirurgie Digestive, AP-HP, Hôpital Louis Mourier, DMU ESPRIT-GHU AP-HP, Nord-Université Paris Cité, Colombes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncisional hernia repairs (IHRs) are not recommended in patients with severe obesity (BMI ≥ 35 kg/m

methodsAll patients planned for IHR with a BMI ≥ 35 kg/m

resultsFifty-two patients in the control group were compared to 24 with GLP-1 agonists. The distribution of GLP-1 agonists was as follows: semaglutide (n = 12; 50%), dulaglutide (n = 7; 29.2%), and liraglutide (n = 5; 20.8%). The mean initial BMI was 40.1 ± 3.6 kg/m

conclusionThis study demonstrated the efficacy of GLP-1 agonists in the optimization of patients with obesity, allowing two thirds of the patients to benefit from IHR, with a tendency for lower morbidity.

trial registrationCPP Mediterranee, n° 21.00430.000004.

Indexed as

Glucagon-Like Peptide-1 Receptor AgonistsHerniorrhaphyIncisional HerniaObesity, MorbidPreoperative CareAdultAgedFemaleGlucagon-Like Peptide 1Glucagon-Like PeptidesHumansLiraglutideMaleMiddle AgedPilot ProjectsTreatment OutcomeGlucagon-Like Peptide 1Glucagon-Like Peptide-1 Receptor AgonistsGlucagon-Like PeptidesLiraglutideGLP‐1 agonistsincisional hernia repairobesityprehabilitationweight loss

Identifiers

PMID40088135
PMCPMC11994139

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.