Evidence map›Paper›PMID 40088307›Full record

ReviewNeuroradiology2025

Advanced targeted microsphere embolization for arteriovenous malformations: state-of-the-art and future directions.

Ali Mortezaei, Khaled M Taghlabi, Nadir Al-Saidi, Saketh Amasa, Rachael E Whitehead, Alex Hoang, Kurt Yaeger, Amir H Faraji, Ramanathan Kadirvel, Sherief Ghozy

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ali MortezaeiGonabad University of Medical Sciences, Gonabad, Iran.
Khaled M Taghlabi *Clinical Innovations Laboratory, Department of Neurological Surgery, Houston Methodist Research Institute, Houston, TX, USA. ktaghlabi@houstonmethodist.org.
Nadir Al-Saidi *College of Medicine, Central Michigan University, Mt Pleasant, MI, USA. alsaidi.nadir@gmail.com.
Saketh AmasaDepartment of Neurosurgery, The University of Texas Medical Branch, Galveston, TX, USA.
Rachael E WhiteheadClinical Innovations Laboratory, Department of Neurological Surgery, Houston Methodist Research Institute, Houston, TX, USA.
Alex HoangDepartment of Neurological Surgery, Houston Methodist Hospital, Houston, TX, USA.
Kurt YaegerDepartment of Neurological Surgery, Houston Methodist Hospital, Houston, TX, USA.
Amir H FarajiClinical Innovations Laboratory, Department of Neurological Surgery, Houston Methodist Research Institute, Houston, TX, USA.
Ramanathan KadirvelDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA.
Sherief GhozyDepartment of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA. ghozy.sherief@mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArteriovenous malformations (AVMs) present a significant therapeutic challenge, as current treatment modalities frequently fail to achieve complete and rapid obliteration and are associated with substantial morbidity in both the short and long term. This underscores the critical need for innovative therapeutic strategies that enable efficient AVM obliteration while minimizing patient risk. The current review aims to comprehensively assess the role of ATME in AVM management, examining its clinical efficacy, associated risks and benefits, and the economic and ethical implications to provide valuable foundation for future studies and guiding development in treatment strategies for AVMs.

resultsAdvanced targeted microsphere embolization (ATME) has emerged as a promising therapeutic option, initially developed for the localized treatment of AVMs and unresectable tumors, including liver cancer. By providing targeted delivery, ATME offers potential advantages over conventional approaches in achieving effective local control.

conclusionsATME are safe and effective for vascular disease and cancer. Although evidence for microspheres in AVMs is scarce, results are promising. Future research could refine eligibility criteria, evaluate treatment techniques, and optimize ATME.

Indexed as

Arteriovenous MalformationsEmbolization, TherapeuticIntracranial Arteriovenous MalformationsMicrospheresHumansTreatment OutcomeAdvanced Targeted Microsphere EmbolizationArteriovenous MalformationMicrosphereTrans-Arterial ChemoembolizationTrans-Arterial Radioembolization

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.