Evidence map›Paper›PMID 40089684›Full record

ArticleBMC plant biology2025

Transcriptomic and metabolomic analysis reveal the cold tolerance mechanism of common beans under cold stress.

Wen Tang, Zixuan Li, Zeping Xu, Xiyu Sui, Le Liang, Jiachang Xiao, Xueping Song, Bo Sun, Zhi Huang, Yunsong Lai and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. MYB transcription factors in plant cold stress adaptation: integrating phylogeny, signaling networks, and metabolic regulation.Physiology and molecular biology of plants : an international journal of functional plant biology · 2026
    Review
  2. Article
  3. Cold Stress Responses and Adaptation Mechanisms inPlants (Basel, Switzerland) · 2026
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Wen Tang *College of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, China.
Zixuan Li *College of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, China.
Zeping XuCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, China.
Xiyu SuiCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, China.
Le LiangCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, China.
Jiachang XiaoCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, China.
Xueping SongCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, China.
Bo SunCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, China.
Zhi HuangCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, China.
Yunsong LaiCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, China.
Changquan WangCollege of Resources, Sichuan Agricultural University, Chengdu, Sichuan, China.
Yi TangCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, China. tangyi@sicau.edu.cn.
Huanxiu LiCollege of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, China. huanxiuli62@163.com.

Funding

Breeding Research in Vegetables Grant No 2021YFYZ0022Sichuan Innovation Team Project of National Modern Agricultural Industry Technology System Grant No SCCXTD-2024-5
6 · The paper itself

Abstract

backgroundCommon bean (Phaseolus vulgaris L.) is a thermophilic crop, and exposure to cold stress can significantly impact their yield and quality. To elucidate the impact of cold stress on cold-tolerant 'Wei Yuan' (WY) and cold-sensitive 'Bai Bu Lao' (BBL) of common bean, the mechanism of cold tolerance was studied by physiological and biochemical and multi-omics analysis.

resultsIn this study, lower relative conductivity and higher malondialdehyde content after cold stress endowed 'WY' seedlings with cold tolerance. A total of 11,837 differentially expressed genes (DEGs) and 923 differential metabolites (DEMs) were identified by transcriptome and metabolomics analysis. Joint analysis showed that under cold stress, DEGs and DEMs in common beans are extensively engaged in sugar, amino acid and isoflavonoid biosynthesis, flavone and flavonol biosynthesis, and plant hormone signal translation, especially related to isoflavone biosynthesis. In addition, it was also found that bHLH and MYB family transcription factors may be involved in the cold signal transduction of common bean.

conclusionsThe above results will provide a theoretical basis for the cold tolerance mechanism of common beans and provide help for the screening of cold-tolerant resources of common beans. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Cold-Shock ResponsePhaseolusTranscriptomeCold TemperatureGene Expression ProfilingGene Expression Regulation, PlantMetabolomeMetabolomicsCold stressIsoflavoneMulti-omicsPlant hormonesSecondary metabolites

Identifiers

PMID40089684
PMCPMC11909926

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.