Evidence mapPaperPMID 40091018Full record

ArticleIslets2025

The effects of free fatty acid-free bovine serum albumin and palmitate on pancreatic β-cell function.

Katherine Sentjens, Renjitha Pillai, Jamie W Joseph

Abstract read
In one paragraph

Article in Islets, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Katherine SentjensSchool of Pharmacy, University of Waterloo, Kitchener, ON, Canada.
Renjitha PillaiSchool of Pharmacy, University of Waterloo, Kitchener, ON, Canada.
Jamie W JosephSchool of Pharmacy, University of Waterloo, Kitchener, ON, Canada.ORCID 0000-0002-6847-534X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic β-cells release insulin in response to fluctuations in plasma glucose, amino acids, and free fatty acids (FFA). Clonal cell lines and isolated islets serve as essential early models for studying the impact of nutrients and evaluating potential therapies to address β-cell dysfunction. Acute and chronic changes in FFA levels have been shown to have positive and negative effects on β-cell function both

Indexed as

Fatty Acids, NonesterifiedInsulin-Secreting CellsPalmitatesSerum Albumin, BovineAnimalsCattleCell LineCells, CulturedHumansInsulinInsulin SecretionFatty Acids, NonesterifiedInsulinPalmitatesSerum Albumin, Bovinealbumininsulin secretionIsletsoxygen consumptionpalmitate

Identifiers

PMID40091018
PMCPMC11917175

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.