ArticleAmerican journal of translational research2025
Differential effects of low- and high-frequency sacral neuromodulation on urinary symptoms: high-frequency improves Qmax, low-frequency enhances bladder capacity.
Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare the efficacy, safety, and patient satisfaction between low- and high-frequency sacral neuromodulation (SNM) in patients undergoing SNM.
methodsThis retrospective study included 263 patients treated between January 2016 and December 2022 at PLA General Hospital of Southern Theater Command. Patients received either low-frequency (≤ 16 Hz) or high-frequency (> 16 Hz) SNM. Urodynamic outcomes, quality of life, adverse events, and patient satisfaction were assessed pre- and post-treatment.
resultsOf the cohort, 128 patients received low-frequency and 135 received high-frequency stimulation. Post-treatment, the high-frequency group showed a significant improvement in maximum urinary flow rate (Qmax) and detrusor contractility compared to the low-frequency group. In contrast, the low-frequency group exhibited greater increases in maximum bladder capacity. Both groups demonstrated significant reductions in urination difficulty and waiting times, with the high-frequency group achieving more pronounced improvements. Quality of life scores and adverse event rates were similar across both groups. High patient satisfaction was noted in both groups, with no significant difference in overall satisfaction rates (P = 0.404). Correlation analysis indicated significant relationships between stimulation frequency and various urodynamic parameters, with higher frequencies generally associated with better urodynamic outcomes.
conclusionBoth low- and high-frequency SNM improve urinary symptoms and quality of life, with high-frequency showing better urodynamic outcomes in Qmax and detrusor contractility, while low-frequency enhances bladder capacity. Both treatments are safe and highly satisfactory to patients.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.