Evidence map›Paper›PMID 40092513›Full record

ArticleIJTLD open2025

Anthropometric growth trajectories of children presenting with presumptive pulmonary TB.

M V de Geus, M van Niekerk, C McKenzie, I Dewandel, J Zenhausern, E Wijstma, R Dunbar, H Rabie, A C Hesseling, V W Jongen and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in IJTLD open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

M V de GeusDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
M van NiekerkDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
C McKenzieDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
I DewandelDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
J ZenhausernDepartment of Paediatrics, Karl Bremer Hospital, Cape Town, South Africa.
E WijstmaDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
R DunbarDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
H RabieDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
A C HesselingDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
V W JongenDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
M M van der ZalmDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Funding

Multiplexed Antigen-Specific Antibody Fc Profiling on a Chip for Point-of-Care Diagnosis of TB in HIV-infected ChildrenR01AI152158 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI BRYSON, BRYAN DAVID · 2020 to 2024
$4.1M
The long-term consequences of pulmonary tuberculosis and respiratory viruses on lung health in young South African childrenK43TW011028 · FIC · STELLENBOSCH UNIVERSITY · PI VAN DER ZALM, MARIEKE MARGREET · 2020 to 2024
$647k
FIC NIH HHS K43 TW011028NIAID NIH HHS R01 AI152158
6 · The paper itself

Abstract

backgroundThis study assessed growth trajectories in children presenting with presumptive pulmonary TB (PTB).

methodsThis sub-study of the Umoya TB diagnostic study was conducted in South Africa from November 2017 until November 2021. Children (0-13 years) with presumptive PTB were recruited from and followed up for 12 months. Anthropometric measurements of children with TB, symptomatic controls (TB excluded), and healthy controls were taken at baseline and follow-up (2, 8, 16, 24 and 52 weeks). Changes in weight-for-age

resultsOf the 372 children included in the analyses (median age: 2 years, IQR 1-4), 153 children had TB, 168 were symptomatic and 51 were healthy controls. Median WAZ was similar between groups; however, more children with TB were underweight than symptomatic and healthy controls. WAZ increased over time for children with TB. Median HAZ of children with TB (-1.34, IQR -2.17 to -0.21) was lower compared to symptomatic (-1.06, IQR -1.90 to -0.10) and healthy controls (-0.74, IQR -1.26 to -0.03;

conclusionTo improve the long-term outcomes of TB and other illnesses, the overall nutrition of children needs to be improved.

Indexed as

growthpaediatricpost-tuberculosisSouth Africatuberculosis

Identifiers

PMID40092513
PMCPMC11906025

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.