Evidence map›Paper›PMID 40092525›Full record

ArticleBioinformatics advances2025

Leveraging LASSO-based methodologies for enhanced SNP analysis in plant genomes.

Nisha Puthiyedth, Farshad Zeinalinesaz, Dongdong Hou, Yue Zhang, Wenjun Lin, Yan Yan

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In one paragraph

Article in Bioinformatics advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nisha PuthiyedthDepartment of Computing Science, Thompson Rivers University, Kamloops, BC V2C 0C8, Canada.
Farshad ZeinalinesazSchool of Computer Science, University of Guelph, Guelph, ON N1G 1Y4, Canada.
Dongdong HouSchool of Computer Science, University of Guelph, Guelph, ON N1G 1Y4, Canada.
Yue ZhangDepartment of Mathematics and Statistics, Thompson Rivers University, Kamloops, BC V2C 0C8, Canada.
Wenjun LinDigital Healthcare Innovation Lab, Faculty of Computer Science & Technology, Algoma University, Brampton, ON L6V 1A3, Canada.
Yan YanSchool of Computer Science, University of Guelph, Guelph, ON N1G 1Y4, Canada.ORCID https://orcid.org/0000-0002-8380-2863

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Summary: Genome-wide association studies (GWAS) have been widely used to reveal the associations between genetic variations and phenotypes in a population of individuals. However, they have been criticized for missing important genetic markers usually due to the fact that the data may not fit the statistical models well. In this study, we address the challenge of identifying significant single nucleotide polymorphisms (SNPs) in GWAS by harnessing the capabilities of two sophisticated regression models, BIGLASSO and AUTALASSO. They are both variants of the least absolute shrinkage and selection operator (LASSO). Our research contributes to the field of genomics through detailed comparative analysis of Availability and implementation: Key results from the paper are available at the https://github.com/DongdongHou006/LASSO-SNP. The program was implementated using Python and R, and was tested using the Digital Research Alliance of Canada.

Identifiers

PMID40092525
PMCPMC11908641

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.