Evidence map›Paper›PMID 40093151›Full record

ArticlebioRxiv : the preprint server for biology2025

Genetic context of transgene insertion can influence neurodevelopment in zebrafish.

Anna J Moyer, Alexia Barcus, Mary E S Capps, Jessica A Chrabasz, Robert L Lalonde, Christian Mosimann, Summer B Thyme

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Anna J MoyerDepartment of Biochemistry and Molecular Biotechnology, The University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.ORCID 0000-0003-1912-1745
Alexia BarcusDepartment of Biochemistry and Molecular Biotechnology, The University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.ORCID 0009-0007-9339-4406
Mary E S CappsDepartment of Biochemistry and Molecular Biotechnology, The University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.ORCID 0009-0005-4222-2300
Jessica A ChrabaszDepartment of Biochemistry and Molecular Biotechnology, The University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.
Robert L LalondeDepartment of Pediatrics, Section of Developmental Biology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, USA.
Christian MosimannDepartment of Pediatrics, Section of Developmental Biology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, USA.ORCID 0000-0002-0749-2576
Summer B ThymeDepartment of Biochemistry and Molecular Biotechnology, The University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.ORCID 0000-0003-3593-4148

Funding

Large-scale Genetic Investigation and Drug Discovery to Counteract Down Syndrome Neural DeficitsR01HD115159 · NICHD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Summer B Thyme · 2024 to 2026
$2.5M
Defining the Chemical Perturbome of Neural Development and ActivityDP2NS132107 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI THYME, SUMMER B · 2022 to 2025
$2.3M
Decoding the transcriptional mechanisms of pericardium formationR01HL168097 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI Christian Mosimann · 2024 to 2026
$1.7M
Mechanisms of human appendicular and cardiovascular comorbidities: An analysis of heterogeneity and lineage trajectories of the lateral plate mesodermK99HL168148 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI LALONDE, ROBERT L · 2023 to 2024
$199k
NHLBI NIH HHS K99 HL168148NHLBI NIH HHS R01 HL168097NICHD NIH HHS R01 HD115159NINDS NIH HHS DP2 NS132107
6 · The paper itself

Abstract

The Gal4/

Indexed as

cell cycleGadd45Gal4/UASneuronal developmentproliferationsci-RNA-seqTol2transgenesiszebrafish

Identifiers

PMID40093151
PMCPMC11908146

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.