Interleukin 26 attenuates osteoblast differentiation in osteoarthritis patients by activating COX2 and NF-κB pathways.

Yi-Hsuan Lin, Yi-Hsun Wang, Yi-Jen Peng, Feng-Cheng Liu, Huey-Kang Sytwu, Chia-Pi Cheng

Abstract read

In one paragraph

Article in International journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

NF-κB signaling in osteoarthritis: integrating mechanical stress, innate immunity, and cartilage degeneration.Frontiers in immunology · 2026
Review
Dynamics of the Interleukin-10 Family of Cytokines in Chronic Otitis Media Patients upon 1,8-Cineol Treatment.In vivo (Athens, Greece)
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yi-Hsuan LinDepartment and Graduate institute of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan.

Yi-Hsun WangGraduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan.

Yi-Jen PengDepartment of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

Feng-Cheng LiuRheumatology/Immunology and Allergy, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

Huey-Kang SytwuNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, Miaoli County, Taiwan; Department of Microbiology and Immunology, National Defense Medical Center, Taipei, Taiwan.

Chia-Pi ChengDepartment and Graduate institute of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cyclooxygenase 2InterleukinsOsteoarthritisOsteoblastsAnimalsCell DifferentiationCell LineCells, CulturedFemaleHumansMaleMiceMiddle AgedNF-kappa BNitric Oxide Synthase Type IISignal TransductionCyclooxygenase 2InterleukinsNF-kappa BNitric Oxide Synthase Type IIPTGS2 protein, humaninterleukin 26osteoarthritisosteoblast differentiation

Identifiers

PMID40093804

DOI10.7150/ijms.102967

PMCPMC11905269

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.