ArticleFrontiers in oncology2025
The velocity of temporalis muscle wasting in cerebral metastasis is prognostic for poor survival.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Reduced Temporal Muscle Thickness Is Associated with Increased Postoperative Complications After Cranioplasty.Journal of clinical medicine · 2026Article
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12 authors.
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Abstract
Purpose: Recently, the temporalis muscle thickness on cranial CT scan was proposed as a surrogate marker for patients' baseline frailty that correlates with outcome in primary and metastatic brain tumor patients. In this study, we investigated whether the velocity of temporalis muscle atrophy (TMA) affects the outcome of patients with cerebral metastases. Methods: We analyzed radiological and clinical data sets of 96 patients who received craniotomy for cerebral metastasis resection in our institution. We then correlated the radiological data with clinical course and outcome after stratification for the velocity of temporalis muscle atrophy. Results: The median velocity of TMA was 0.0016 mm/day. In patients with a slow TMA rate, the median overall survival was significantly longer than in patients with a fast TMA rate (37.7 months versus 22.9, Conclusion: Based on this study, the velocity of temporalis muscle atrophy may represent an objective and dynamic index with potential for survival prognostication for patients with cerebral metastases.
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