Evidence map›Paper›PMID 40097231›Full record

ArticleBMJ open2025

Predictive factors of sexual dysfunction and quality of life among type 2 diabetes outpatients in southern Iran: a cross-sectional survey.

Vahid Keshtkar, Mina Zarmehrparirouy, Mohammad Ali Izadi, Mohammad Hossein Sharifi

Abstract readMulticenter Study
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Vahid KeshtkarDepartment of Community Medicine, Shiraz University of Medical Sciences, Shiraz, Iran (the Islamic Republic of).ORCID http://orcid.org/0000-0001-5293-724X
Mina ZarmehrparirouyDepartment of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran (the Islamic Republic of).ORCID http://orcid.org/0000-0002-4226-7331
Mohammad Ali IzadiShiraz University of Medical Sciences, Shiraz, Iran (the Islamic Republic of).
Mohammad Hossein SharifiResearch Center for Traditional Medicine and History of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran (the Islamic Republic of) mhsharifi1350@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study was conducted to determine the predictors of sexual dysfunction and quality of life (QOL) in patients with type 2 diabetes (T2D). Sexual dysfunction is a long-term consequence of diabetes that is widely ignored in personal management, even though it can have an adverse effect on QOL.

designThis research was designed as a cross-sectional study.

setting12 diabetes centres and clinics in Shiraz, south of Iran.

participants390 male patients with T2D mellitus participated in this project. The inclusion criteria were being 30-65 years, having a history of diabetes of at least 1 year, having fasting blood sugar and glycosylated haemoglobin tests and being willing to participate in the study. Patients with medication treatment for mental disorders, a history of heart disease and renal failure were excluded. PRIMARY OUTCOME MEASURES: QOL and erectile dysfunction (ED). The questionnaires were the Audit of Diabetes-Dependent QOL (ADDQOL) and the International Index of Erectile Function (IIEF-15). Data were reported using descriptive and analytical statistics methods.

resultThe participants' mean age was 48.35±9.27 years. The average weighted impact (AWI) score of ADDQOL for the participants was -3.01, indicating the negative influence of diabetes on their QOL. The mean value of the total score of sexual dysfunction was 42.79±22.75, and the rates of mild, mild to moderate, moderate and severe ED were 19%, 17.7%, 17.2% and 24.6%, respectively. Sexual dysfunction was significantly related to age (OR=1.06; 95% CI: 1.02 to 1.09), diabetes duration (OR=1.04, 95% CI: 1.01 to 1.07), HbA1c (OR=1.45, 95% CI: 1.07 to 1.95), BMI (OR=1.10, 95% CI: 1.03 to 1.16), marital status (married: OR=2.30, 95% CI: 1.40 to 3.77), without diabetes complication (OR=0.17, 95% CI: 0.08 to 0.31) and insulin therapy (OR=2.86, 95% CI: 1.67 to 4.92). ADDQOL was significantly related to age (OR=1.049), HbA1c (OR=2.192), marital status (married: OR=2.089), educational level (high school certificate: OR=0.337, university degree: OR=0.295), diabetes complication (no complication: OR=0.372) and insulin therapy (OR=3.82). AWI was correlated with the total score of IIEF-15 (r=0.78, p value <0.001).

conclusionTo improve the QOL of diabetic patients, it is suggested that all the predictors of sexual dysfunction, such as glycaemic control, obesity, diabetes complications and duration, should be considered in diabetic management guidelines.

Indexed as

Diabetes Mellitus, Type 2Erectile DysfunctionQuality of LifeSexual Dysfunction, PhysiologicalAdultAgedCross-Sectional StudiesGlycated HemoglobinHumansIranMaleMiddle AgedOutpatientsRisk FactorsSurveys and QuestionnairesGlycated HemoglobinErectile dysfunctionGeneral diabetesQuality of Life

Identifiers

PMID40097231
PMCPMC11927430

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.