Evidence map›Paper›PMID 40098478›Full record

ReviewImmunotherapy2025

Optimizing TIL therapy for uveal melanoma: lessons learned and unlearned from cutaneous melanoma.

Shravan Leonard-Murali, Udai S Kammula

Abstract readReview
In one paragraph

Review in Immunotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shravan Leonard-MuraliSolid Tumor Cellular Immunotherapy Program, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.
Udai S KammulaSolid Tumor Cellular Immunotherapy Program, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.

Funding

Postdoctoral Research Training in Biotherapy of CancerT32CA113263 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Udai S Kammula · 2006 to 2026
$3.6M
Metabolic Reprogramming of Tumor Infiltrating Lymphocytes for Adoptive ImmunotherapyR01CA233521 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAMMULA, UDAI S · 2019 to 2023
$1.8M
NCI NIH HHS R01 CA233521NCI NIH HHS T32 CA113263
6 · The paper itself

Abstract

Adoptive transfer of tumor infiltrating lymphocytes (TIL-ACT) is a personalized cancer therapy that harnesses the anti-tumor activity of tumor resident T cells through

Indexed as

Immunotherapy, AdoptiveLymphocytes, Tumor-InfiltratingMelanomaSkin NeoplasmsUveal NeoplasmsCutaneous Malignant MelanomaHumansUveal Melanomaadoptive cell therapyimmune checkpoint inhibitionimmune exclusionimmunotherapytumor infiltrating lymphocytesUveal melanoma

Identifiers

PMID40098478
PMCPMC12013418

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.