Evidence mapPaperPMID 40098694Full record

ReviewRSC advances2025

Breaking barriers in cancer diagnosis: unveiling the 4Ms of biosensors.

Sachin Gupta, Vijay Mishra, Alaa A A Aljabali, Aqel Albutti, Rajeev Kanday, Mohamed El-Tanani, Yachana Mishra

Abstract readReview
In one paragraph

Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sachin GuptaDepartment of Robotics and Control Engineering, School of Electronics and Electrical Engineering, Lovely Professional University Phagwara Punjab-144411 India.
Vijay MishraSchool of Pharmaceutical Sciences, Lovely Professional University Phagwara Punjab-144411 India.ORCID https://orcid.org/0000-0001-6542-2464
Alaa A A AljabaliDepartment of Pharmaceutics & Pharmaceutical Technology, Yarmouk University Irbid Jordan alaaj@yu.edu.jo.ORCID https://orcid.org/0000-0002-9519-6338
Aqel AlbuttiDepartment of Basic Health Sciences, College of Applied Medical Sciences, Qassim University Buraydah 51452 Saudi Arabia.
Rajeev KandaySchool of Computer Science and Engineering, Lovely Professional University Phagwara Punjab-144411 India.ORCID https://orcid.org/0000-0003-2569-1891
Mohamed El-TananiRas Al Khaimah Medical and Health Sciences University Ras Al Khaimah United Arab Emirates.
Yachana MishraSchool of Bioengineering and Biosciences, Lovely Professional University Phagwara Punjab-144411 India yachanamishra@gmail.com.ORCID https://orcid.org/0000-0002-3467-0518

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer, an insidious affliction, continues to exact a heavy toll on humanity, necessitating early detection and nuanced comprehension of its intricacies for effective treatment. Recent strides in micro and nanoscale electronic chip fabrication have revolutionized biosensor technology, offering promising avenues for biomedical and telemedicine applications. Micro Electromechanical System (MEMS)-based integrated circuits (ICs) represent a paradigm shift in detecting chemical and biomolecular interactions pertinent to cancer diagnosis, supplanting conventional methodologies. Despite the wealth of research on biosensors, a cohesive framework integrating Material, Mechanism, Modeling, and Measurement (4M) dimensions is often lacking. This review aims to synthesize these dimensions, exploring recent breakthroughs in biosensor design and development. Categorized based on electromechanical integration, material selection, and fabrication processes, these biosensors bridge crucial knowledge gaps within the research community. A comparative analysis of sensing methods in point-of-care (PoC) technology provides insights into their practicality and efficacy. Moreover, we critically evaluate biosensor limitations, pivotal in addressing challenges hindering their global commercialization.

Identifiers

PMID40098694
PMCPMC11912004

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.