Evidence map›Paper›PMID 40099236›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2025

Age-Related Macular Degeneration and Circadian Preference.

Estefany Garces, Katarzyna Slota, Michael W Stewart, Maria P Guzman, Natalia M Werninck, Pablo R Castillo

Abstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Estefany GarcesDivision of Pulmonary, Allergy and Sleep Medicine, Mayo Clinic College of Medicine and Science, Jacksonville, FL, USA.ORCID 0000-0003-0316-0360
Katarzyna SlotaNorthwest Community Healthcare, Schaumburg, IL, USA.
Michael W StewartDivision of Ophthalmology, Mayo Clinic College of Medicine and Science, Jacksonville, FL, USA.
Maria P GuzmanSleep & Obesity Medicine, St Petersburg, FL, USA.
Natalia M WerninckDivision of Pulmonary, Allergy and Sleep Medicine, Mayo Clinic College of Medicine and Science, Jacksonville, FL, USA.
Pablo R CastilloDivision of Pulmonary, Allergy and Sleep Medicine, Mayo Clinic College of Medicine and Science, Jacksonville, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Age-related macular degeneration (AMD) is the leading cause of blindness in developed nations. Within the retina, a subset of cells, called Patients and Methods: The Horne-Östberg Morningness-Eveningness questionnaire was administered to previously screened patients with wet AMD who received bilateral anti-vascular endothelial growth factor eye injections (study participants) as well as those without eye pathology (controls). Thirty-one study participants and 19 controls completed the survey and were included in the analysis. We used Wilcoxon rank sum test and Fisher exact test for continuous and categorical variables respectively. Results: Study participants had a higher median age compared to controls (83 vs 75, Conclusion: In this pilot study, study participants encountered greater challenges with morning exercise compared to controls. Nonetheless, there was no significant difference in chronotype between study participants and controls. The study could serve as a foundation for more extensive research exploring the interplay between vision loss and circadian rhythms.

Indexed as

chronotypescircadian rhythmmaculopathypilot studyretinal ganglion cellssurveys and questionnaires

Identifiers

PMID40099236
PMCPMC11912916

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.