Evidence map›Paper›PMID 40100943›Full record

ArticleCirculation. Cardiovascular imaging2025

Prognosis and Risk Stratification in Dilated Cardiomyopathy With LVEF≤35%: Cardiac MRI Insights for Better Outcomes.

Di Zhou, Leyi Zhu, Shuang Li, Weichun Wu, Baiyan Zhuang, Jing Xu, Wenjing Yang, Jian He, Yining Wang, Yuhui Zhang and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation. Cardiovascular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Di Zhou *Department of Magnetic Resonance Imaging (D.Z., L.Z., S.L., B.Z., J.X., W.Y., J.H., Y.W., S.Z., M.L.), Fuwai Hospital and National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID 0000-0002-9766-860X
Leyi Zhu *Department of Magnetic Resonance Imaging (D.Z., L.Z., S.L., B.Z., J.X., W.Y., J.H., Y.W., S.Z., M.L.), Fuwai Hospital and National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Shuang LiDepartment of Magnetic Resonance Imaging (D.Z., L.Z., S.L., B.Z., J.X., W.Y., J.H., Y.W., S.Z., M.L.), Fuwai Hospital and National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID 0000-0002-0750-5779
Weichun WuDepartment of Echocardiography (W.W.), Fuwai Hospital and National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID 0000-0001-8898-6078
Baiyan ZhuangDepartment of Magnetic Resonance Imaging (D.Z., L.Z., S.L., B.Z., J.X., W.Y., J.H., Y.W., S.Z., M.L.), Fuwai Hospital and National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID 0000-0003-3054-5514
Jing XuDepartment of Magnetic Resonance Imaging (D.Z., L.Z., S.L., B.Z., J.X., W.Y., J.H., Y.W., S.Z., M.L.), Fuwai Hospital and National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID 0000-0003-1350-4489
Wenjing YangDepartment of Magnetic Resonance Imaging (D.Z., L.Z., S.L., B.Z., J.X., W.Y., J.H., Y.W., S.Z., M.L.), Fuwai Hospital and National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jian HeDepartment of Magnetic Resonance Imaging (D.Z., L.Z., S.L., B.Z., J.X., W.Y., J.H., Y.W., S.Z., M.L.), Fuwai Hospital and National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID 0000-0001-6899-5145
Yining WangDepartment of Magnetic Resonance Imaging (D.Z., L.Z., S.L., B.Z., J.X., W.Y., J.H., Y.W., S.Z., M.L.), Fuwai Hospital and National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID 0000-0003-3288-7921
Yuhui ZhangDepartment of Heart Failure (Y.Z.), Fuwai Hospital and National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID 0000-0002-2382-8869
Guanshu LiuRussell H. Morgan Department of Radiology and Radiological Sciences, Division of MR Research, The Johns Hopkins University School of Medicine, Baltimore, MD (G.L.).ORCID 0000-0002-8188-4332
Xiaoxin SunDepartment of Nuclear Medicine (X.S.), Fuwai Hospital and National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Qiang ZhangOxford Centre for Clinical Magnetic Resonance Research (OCMR), Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, United Kingdom (Q.Z.).ORCID 0000-0003-3385-1242
Zhongzhao TengDepartment of Life and Health Science, Fuyao University of Science and Technology, Fujian, China (Z.T.).ORCID 0000-0003-3973-6157
Arlene SirajuddinNational Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD (A.S.).
Andrew E AraiDivision of Cardiovascular Medicine and Department of Radiology, University of Utah School of Medicine, Salt Lake City, Utah, USA (A.E.A.).ORCID 0000-0002-5413-1466
Shihua ZhaoDepartment of Magnetic Resonance Imaging (D.Z., L.Z., S.L., B.Z., J.X., W.Y., J.H., Y.W., S.Z., M.L.), Fuwai Hospital and National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Minjie LuDepartment of Magnetic Resonance Imaging (D.Z., L.Z., S.L., B.Z., J.X., W.Y., J.H., Y.W., S.Z., M.L.), Fuwai Hospital and National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID 0000-0001-8696-318X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrent guidelines recommend implantable cardioverter defibrillators for the primary prevention of sudden cardiac death (SCD) in patients with dilated cardiomyopathy with left ventricular ejection fraction (LVEF)≤35%. However, its effectiveness is hindered by the inability to reliably discriminate between the risk of SCD and competing death of heart failure deterioration, thereby limiting its clinical utility. We aimed to refine the SCD risk stratification model based on cardiac magnetic resonance imaging for patients with dilated cardiomyopathy with LVEF≤35%.

methodsA total of 1272 patients with dilated cardiomyopathy with LVEF≤35% who underwent cardiac magnetic resonance imaging were consecutively enrolled in this study. The primary end point is a composite of SCD or aborted SCD and the second end point is a composite of heart failure death and heart transplantation.

resultsOver a median follow-up of 86.3 months, 101 patients reached the primary end point. In the adjusted analysis, age (hazard ratio [HR], 1.02 [95% CI, 1.01-1.04];

conclusionsPatients with dilated cardiomyopathy with late gadolinium enhancement≥7.5% were at heightened risk of SCD events, which can be used for risk assessment. Risk stratifications for SCD, combining clinical and cardiac magnetic resonance imaging may potentially guide decision-making for implantable cardioverter defibrillator therapy.

Indexed as

Cardiomyopathy, DilatedDeath, Sudden, CardiacMagnetic Resonance Imaging, CineStroke VolumeVentricular Function, LeftAdultAgedDefibrillators, ImplantableFemaleHeart FailureHeart TransplantationHumansMaleMiddle AgedPredictive Value of TestsPrognosiscardiomyopathy, dilateddeath, sudden, cardiacdefibrillators, implantableheart failureheart transplantationmagnetic resonance imaging

Identifiers

PMID40100943
PMCPMC11913248

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.