ArticleAnalytical chemistry2025
Cross-Scale Multimodal Imaging for Organic Matter in Extraterrestrial Samples.
Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Quantifying Trace Metals in Gunflint Microfossils by 3D Correlative X-ray Nanoimaging.Analytical chemistry · 2026Article
- Impact-processed nitrogen-bearing organics in Chang'e-5 and Chang'e-6 lunar regolith.Science advances · 2026Article
- Very long chain sphingolipids govern brain myelination by regulating oligodendrocyte differentiation and membrane microdomain integrity.Journal of translational medicine · 2026Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The analysis of extraterrestrial organic matter in samples returned by space missions provides a unique opportunity to study prebiotic chemistry. A comprehensive understanding of the occurrence and composition of organic matter is fundamental to unraveling its origin and evolutionary history. However, the scarcity and complexity of these materials pose considerable analytical challenges. Here, we developed a cross-scale multimodal imaging workflow that integrated mass spectrometry imaging (MSI) and vibrational spectroscopy imaging, including desorption electrospray ionization coupled quadrupole-time-of-flight mass spectrometry (DESI-Q-TOF/MS), time-of-flight secondary ion mass spectrometry (TOF-SIMS), nanoscale secondary ion mass spectrometry (NanoSIMS), focal plane array-Fourier transform infrared spectroscopy (FPA-FTIR), and optical photothermal infrared spectroscopy (O-PTIR). This workflow was applied to the Murchison meteorite, with the objective of establishing spatial associations between mineral phases, molecular composition, functional groups, and isotopic composition on a scale from the millimeter to the submicron. The spatial resolution of DESI has been improved from 100 to 200 to 20 μm, enabling spatial correlation with other imaging techniques. For the first time, the enrichment of organic matter─including CHN, CHO, and CHNO compounds and polycyclic aromatic hydrocarbons (PAHs)─in fine-grained rims (FGRs) surrounding silicate chondrules has been observed. Furthermore, the cross-scale multimodal imaging also reveals differences in organic matter composition between Ca-carbonate and phyllosilicates, as well as spatial heterogeneity within the latter. This workflow provides a new paradigm for studying the complex occurrence and composition of organic matter in various research fields, enhancing our understanding of prebiotic materials in the solar system.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.