Evidence map›Paper›PMID 40102471›Full record

ArticleScientific reports2025

Association between the oxidative balance score and mortality in patients with metabolic syndrome.

Yu-Qing Li, Ping Li, Ran Chu, Wei-Wei Tian, Jia-Xin Wang, Yin Liu, Jing Gao

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yu-Qing LiClinical School of Thoracic, Tianjin Medical University, No.22 Qi Xiangtai Road, Heping District, Tianjin, 300070, People's Republic of China.
Ping LiClinical School of Thoracic, Tianjin Medical University, No.22 Qi Xiangtai Road, Heping District, Tianjin, 300070, People's Republic of China.
Ran ChuClinical School of Thoracic, Tianjin Medical University, No.22 Qi Xiangtai Road, Heping District, Tianjin, 300070, People's Republic of China.
Wei-Wei TianClinical School of Thoracic, Tianjin Medical University, No.22 Qi Xiangtai Road, Heping District, Tianjin, 300070, People's Republic of China.
Jia-Xin WangClinical School of Thoracic, Tianjin Medical University, No.22 Qi Xiangtai Road, Heping District, Tianjin, 300070, People's Republic of China.
Yin LiuCardiovascular Institute, Tianjin Chest Hospital, No.261 Tai Erzhuang Road, Jinnan District, Tianjin, 300222, People's Republic of China.
Jing GaoClinical School of Thoracic, Tianjin Medical University, No.22 Qi Xiangtai Road, Heping District, Tianjin, 300070, People's Republic of China. gaojing2088@163.com.

Funding

The Key Project of Scientific and Technological Support Plan of Tianjin in 2020 No. 20YFZCSY00820The Tianjin Health Research Project No. TJWJ2022XK032
6 · The paper itself

Abstract

Anti-oxidant/Pro-oxidant oxidant imbalance leads to chronic inflammation and insulin resistance can lead to the development of metabolic syndrome (MetS). The oxidative balance score (OBS) is a tool for assessing oxidative stress associated with MetS risk. However, the association between OBS and mortality in patients with MetS remains unclear. This study analyzed 10,647 MetS patients from the 1999-2018 National Health and Nutrition Examination Survey (NHANES). OBS were calculated using a combination of 16 dietary and 4 lifestyle factors. Multivariate Cox proportional hazards regression models, Kaplan-Meier survival analysis, restricted cubic splines (RCS), and subgroup analyses were used to evaluate the potential association between OBS and the risk of all-cause and cardiovascular mortality. Sensitivity analyses confirmed the robustness of the results. This study found that OBS was inversely associated with all-cause and cardiovascular mortality in patients with MetS, a result consistent across most subgroups. Both the Kaplan-Meier curve and RCS analysis supported these findings. Sensitivity analysis was used to verify the robustness of the results. Maintaining an antioxidant-based diet and lifestyle may help reduce the risk of all-cause and cardiovascular mortality in patients with MetS. These findings underscore the significance of incorporating antioxidant-rich dietary patterns and behavioral practices in strategies aimed at preventing and managing MetS.

Indexed as

Metabolic SyndromeOxidative StressAdultAgedAntioxidantsCardiovascular DiseasesFemaleHumansKaplan-Meier EstimateLife StyleMaleMiddle AgedNutrition SurveysProportional Hazards ModelsRisk FactorsAntioxidantsMetabolic syndromeMortalityNHANESNutritionOxidative balance scores

Identifiers

PMID40102471
PMCPMC11920368

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.