Evidence mapPaperPMID 40103962Full record

ArticleInternational journal of ophthalmology2025

Renal dysfunction associated with clinical response to intravitreal conbercept therapy for diabetic macular edema.

Wei Wu, Hui-Dong Liu, Xue Xiao, Ya-Xin Wang, Song-Fu Feng, Jia-Qi Liu, Yong-Gang Yuan, Xiao-He Lu

Abstract read
In one paragraph

Article in International journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Recent advances in the study of Conbercept for diabetic macular edema.International journal of retina and vitreous · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei WuDepartment of Ophthalmology, GuangZhou Red Cross Hospital of Jinan University, Guangzhou 510000, Guangdong Province, China.
Hui-Dong LiuDepartment of Ophthalmology, Zhujiang Hospital of Southern Medical University, Guangzhou 510280, Guangdong Province, China.
Xue XiaoDepartment of Ophthalmology, Zhujiang Hospital of Southern Medical University, Guangzhou 510280, Guangdong Province, China.
Ya-Xin WangDepartment of Ophthalmology, Zhujiang Hospital of Southern Medical University, Guangzhou 510280, Guangdong Province, China.
Song-Fu FengDepartment of Ophthalmology, Zhujiang Hospital of Southern Medical University, Guangzhou 510280, Guangdong Province, China.
Jia-Qi LiuDepartment of Ophthalmology, Zhujiang Hospital of Southern Medical University, Guangzhou 510280, Guangdong Province, China.
Yong-Gang YuanDepartment of Ophthalmology, GuangZhou Red Cross Hospital of Jinan University, Guangzhou 510000, Guangdong Province, China.
Xiao-He LuDepartment of Ophthalmology, Zhujiang Hospital of Southern Medical University, Guangzhou 510280, Guangdong Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the impact of renal dysfunction on clinical response to intravitreal conbercept injection (IVC) for diabetic macular edema (DME).

methodsThis retrospective study included a total of 100 eyes from 100 patients with DME treated with IVC with 3+PRN regimen. Based on the estimated glomerular filtration rate (eGFR), the patients were divided into normal renal function group (

resultsThe mean follow-up time was 3.9mo. The mean number of IVCs was 2.07±1.22 in the three groups. Mean BCVA improved significantly from 0.81±0.49 logMAR at baseline to 0.72±0.52 logMAR in the three groups at the final visit (

conclusionOur results indicate that the renal dysfunction is the risk factor associated with the efficacy of IVC for DME.

Indexed as

conberceptdiabetic macular edemarenal dysfunction

Identifiers

PMID40103962
PMCPMC11865644

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.