Evidence map›Paper›PMID 40104464›Full record

ReviewCureus2025

Dumping Syndrome and Bile Acid Reflux Following Pyloroplasty and Gastric Peroral Endoscopic Myotomy (G-POEM) for Refractory Gastroparesis: A Systematic Review.

Ryan Shargo, Isaac Poonen-Honig, Camille Thélin, Christopher G DuCoin, Rahul Mhaskar, Salvatore Docimo, Joseph A Sujka

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ryan ShargoDepartment of Medical Education, University of South Florida Morsani College of Medicine, Tampa, USA.
Isaac Poonen-HonigDepartment of Medical Education, University of South Florida Morsani College of Medicine, Tampa, USA.
Camille ThélinDepartment of Gastroenterology, University of South Florida Morsani College of Medicine, Tampa, USA.
Christopher G DuCoinDepartment of Surgery, University of South Florida Morsani College of Medicine, Tampa, USA.
Rahul MhaskarDepartment of Medical Education, University of South Florida Morsani College of Medicine, Tampa, USA.
Salvatore DocimoDepartment of Surgery, University of South Florida Morsani College of Medicine, Tampa, USA.
Joseph A SujkaDepartment of Surgery, University of South Florida Morsani College of Medicine, Tampa, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment options for medication- and diet-resistant gastroparesis include drainage procedures such as pyloroplasty and gastric peroral endoscopic myotomy (G-POEM). While dumping syndrome (DS) and bile acid gastritis (BAG) have been documented as complications following pyloric drainage procedures, limited evidence exists concerning their incidence after pyloroplasty and G-POEM for refractory gastroparesis. We performed a systematic review of outcomes following pyloroplasty and G-POEM for refractory gastroparesis (PROSPERO: CRD42024559654). PubMed, Embase, Cochrane, and Web of Science databases were systematically searched for articles reporting rates of DS and BAG following pyloric drainage procedures. Assessed outcomes included rates of DS and BAG. Results were narratively synthesized and presented descriptively. Of the 2278 records reviewed, 10 studies were included. Six studies evaluated pyloroplasty, and four studies evaluated G-POEM. Nine studies reported incidence of DS, and two studies reported rates of BAG. The incidence of DS ranged from 0% to 23.1%, with a median incidence of 3.23% and an interquartile range of 6.95% among nine studies. The incidence of BAG ranged from 0% to 15.4% in two studies. The studies displayed high heterogeneity in study design, patient population, and co-interventions, precluding collective data analysis and limiting generalizability. All studies displayed a moderate to serious risk of bias. There exists a paucity of data regarding the incidence of DS and BAG following pyloroplasty and G-POEM for refractory gastroparesis. Despite the theoretical association of these complications with pylorus-modifying procedures, our findings suggest that they may be uncommon or underreported in the treatment of refractory gastroparesis. Improved reporting of these outcomes and robust prospective studies investigating the incidence of such complications are required.

Indexed as

bile acid gastritisbile acid refluxdumping syndromegastric peroral endoscopic myotomygastroparesis treatmentgpoempyloroplasty

Identifiers

PMID40104464
PMCPMC11914853

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.