Evidence map›Paper›PMID 40106351›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Ryosuke Yamamoto, Yui Sahashi, Rieko Shimo-Kon, Miho Sakato-Antoku, Miyuka Suzuki, Leo Luo, Hideaki Tanaka, Takashi Ishikawa, Toshiki Yagi, Stephen M King and 2 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ryosuke Yamamoto *Department of Biological Sciences, Graduate School of Science, Osaka University, Osaka 560-0043, Japan.ORCID 0000-0002-5282-2343
Yui Sahashi *Department of Biological Sciences, Graduate School of Science, Osaka University, Osaka 560-0043, Japan.
Rieko Shimo-Kon *Department of Biological Sciences, Graduate School of Science, Osaka University, Osaka 560-0043, Japan.
Miho Sakato-Antoku *Department of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, CT 06030-3305.ORCID 0009-0000-1397-171X
Miyuka SuzukiDepartment of Biological Sciences, Graduate School of Science, Osaka University, Osaka 560-0043, Japan.
Leo LuoDepartment of Biology and Chemistry, Paul Scherrer Institute, Villigen 5232, Switzerland.ORCID 0009-0006-3328-9359
Hideaki TanakaInstitute for Protein Research, Osaka University, Osaka 565-0871, Japan.
Takashi IshikawaDepartment of Biology and Chemistry, Paul Scherrer Institute, Villigen 5232, Switzerland.ORCID 0000-0002-1976-7477
Toshiki YagiDepartment of Life and Environmental Sciences, Faculty of Bioresource Sciences, Prefectural University of Hiroshima, Hiroshima 727-0023, Japan.ORCID 0000-0002-1379-460X
Stephen M KingDepartment of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, CT 06030-3305.ORCID 0000-0002-5484-5530
Genji KurisuDepartment of Biological Sciences, Graduate School of Science, Osaka University, Osaka 560-0043, Japan.ORCID 0000-0002-5354-0807
Takahide KonDepartment of Biological Sciences, Graduate School of Science, Osaka University, Osaka 560-0043, Japan.

Funding

The Biology of Motile CiliaR35GM140631 · NIGMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI Stephen M King · 2021 to 2026
$4.2M
Chubei Itoh Foundation N/AMEXT | Japan Society for the Promotion of Science (JSPS) Grant-in-Aid for Scientific Research (C) (JP20K06622 and JP24K09454)MEXT | Japan Society for the Promotion of Science (JSPS) Grant-in-Aid for Young Scientists (B) (JP17K15117)MEXT | Japan Society for the Promotion of Science (JSPS) JSPS Grant-in-Aid for Fund for the Promotion of Joint International Research (JP21KK0125)MEXT | Japan Society for the Promotion of Science (JSPS) JSPS Grant-in-Aid for Scientific Research (B) (JP18H02390)MEXT | Japan Society for the Promotion of Science (JSPS) JSPS Grant-in-Aid for Scientific Research (B) (JP23K23190)MEXT | Japan Society for the Promotion of Science (JSPS) JSPS Grant-in-Aid for Scientific Research (B) (JP26291034 and JP17H03665)MEXT | Japan Society for the Promotion of Science (JSPS) JSPS Grant-in-Aid for Scientific Research (C) (JP23K05723)NIGMS NIH HHS R35 GM140631NIH HHS GM140631Swiss National Science Foundation IZLIZ3_200294Uehara Memorial Foundation (UMF) N/A
6 · The paper itself

Abstract

Motile cilia are organelles found on many eukaryotic cells that play critical roles in development and fertility. Human CFAP298 has been implicated in the transport/assembly of ciliary dyneins, and defects in this protein cause primary ciliary dyskinesia. However, neither the exact function nor the structure of CFAP298 have been elucidated. Here, we took advantage of

Indexed as

Algal ProteinsChlamydomonasChlamydomonas reinhardtiiCiliaCytoplasmDyneinsPlant ProteinsUbiquitinCrystallography, X-RayHumansMutationAlgal ProteinsDyneinsPlant ProteinsUbiquitinCFAP298 (DNAAF16/C21ORF59)ciliadyneinFBB18 (DAB2)ubiquitin

Identifiers

PMID40106351
PMCPMC11962417

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.