SynthesisLasers in medical science2025
Effect of high-intensity laser therapy and photobiomodulation therapy on oral lichen planus-a systematic review and meta-analysis.
Synthesis in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Curcumin Versus Corticosteroids for Symptomatic Oral Lichen Planus: A Systematic Review and Meta-Analysis.Clinical and experimental dental research · 2025Pooled it
- Clinical Efficacy and Safety of Photobiomodulation Therapy for Orofacial Conditions in Older Adults: A Systematic Review of Randomized Controlled Trials.Dentistry journal · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study evaluates the efficacy and safety of High-Intensity Laser Therapy (HILT) and Photobiomodulation (PBM) in treating Oral Lichen Planus (OLP), and explores optimal PBM parameter settings. A search of PubMed, Embase, Cochrane Library, Web of Science, CNKI, and SinoMed was conducted for randomized controlled trials (RCTs) on laser therapy for OLP up to October 30, 2024. Study quality was assessed using the Cochrane risk of bias tool and the Jadad score. Eighteen studies were identified, with 16 involving 742 participants included in the meta-analysis. Eleven studies compared PBM with topical corticosteroids (TCS), and five compared HILT with TCS. HILT provided superior pain relief compared to TCS (SMD = -0.51, 95% CI [-0.79,-0.23]), while PBM showed comparable outcomes (SMD = -0.41, 95% CI [-0.87, 0.04]). PBM was more effective at pain relief with total energy density below 120 J/cm
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.