ArticleNature2025
Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium.
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In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Dysfunctional adipose tissue-lymphatic crosstalk in obesity.Nature reviews. Endocrinology · 2026Review
- A Versatile Microfluidic Extrusion-Based Hydrogel Platform for Self-Organization and Long-Term Maintenance of Engineered 3D Lymphatic Endothelium.Advanced healthcare materials · 2026Article
- The crosstalk between lymphatic endothelial cells and immune cells in Physiological and Pathological conditions.Cellular and molecular life sciences : CMLS · 2026Review
- Sliding into Place: The Lymphatic Vessel Endothelial Hyaluronan Receptor LYVE-1 and Its Role as a Mediator of Cell Entry and Trafficking in the Lymphatics.Biomolecules · 2026Review
- Live imaging of vascular dynamics in mouse skin.The Journal of investigative dermatology · 2026Article
- Adhesion G protein-coupled receptors.Pharmacological reviews · 2026Review
- Article
- Bioengineered Lymphatic Vessels in Synthetic Matrices to Study Breast Cancer Cell Functions.Advanced healthcare materials · 2026Article
- From recognition to response: integrated signaling pathways determining pollen acceptance and rejection in Brassicaceae.The New phytologist · 2026Review
- UBC9-mediated SUMOylation of CORO1C drives lung adenocarcinoma progression via Arp2/3-dependent cytoskeletal remodeling.Cell death & disease · 2026Article
- An epithelial morphogenetic program for maximal urine concentration.Nature communications · 2026Article
- The spinal lymphatic system: an emerging pathway bridging fluid homeostasis, immunity, and disease.Bone research · 2026Review
- Lymphatics-on-a-chip microphysiological system: engineering lymphatic structure and functionLab on a chip · 2026Review
- Cooperative ETS transcription factors are required for lymphatic endothelial cell integrity and resilience.The Journal of clinical investigation · 2026Article
- Discovery of Abundant Nano-scale Lymphatic-like Vessels in Brains.bioRxiv : the preprint server for biology · 2026Article
- Transcriptomics- and 3D imaging-based characterization of the lymphatic vasculature in human skin.The Journal of experimental medicine · 2026Article
- Normal cardiac lymphatics and their mimics.American journal of physiology. Heart and circulatory physiology · 2026Article
- Lung Lymphatics in Edema, Inflammation, and Thrombosis.Arteriosclerosis, thrombosis, and vascular biology · 2025Review
- Dynamics of brain valves: ostensible rectification mechanisms for cerebrospinal fluid flow.Journal of the Royal Society, Interface · 2025Article
- Intestinal lymphatic vasculature is functionally adapted to different drainage regions and is altered by helminth infection.The Journal of experimental medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors.
Hans Schoofs *Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.ORCID 0000-0003-3429-912X
Nina Daubel *Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Sarah SchnabellehnerDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.ORCID 0000-0003-0558-9339
Max L B GrönlohDepartment of Medical Biochemistry at the Amsterdam UMC, location AMC, Amsterdam, The Netherlands.ORCID 0000-0003-0109-8225
Sebastián Palacios MartínezDepartment of Molecular Cytology, Leeuwenhoek Centre for Advanced Microscopy at Swammerdam Institute for Life Sciences at the University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0001-6626-5798
Aleksi HalmeTranslational Cancer Medicine Program and Department of Biochemistry and Developmental Biology, University of Helsinki, Helsinki, Finland.ORCID 0009-0001-2835-0796
Amanda M MarksDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-3961-8831
Marie JeanssonDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.ORCID 0000-0003-1075-8563
Sara BarcosTheodor Kocher Institute, University of Bern, Bern, Switzerland.
Cord BrakebuschBiotech Research and Innovation Center, University of Copenhagen, Copenhagen, Denmark.
Rui BeneditoCentro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.ORCID 0000-0003-2458-3055
Britta EngelhardtTheodor Kocher Institute, University of Bern, Bern, Switzerland.ORCID 0000-0003-3059-9846
Dietmar VestweberMax Planck Institute for Molecular Biomedicine, Münster, Germany.ORCID 0000-0002-3517-732X
Konstantin GaengelDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Fabian LinsenmeierInstitute of Medical Biotechnology, Department of Chemical and Biological Engineering, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
Sebastian SchürmannInstitute of Medical Biotechnology, Department of Chemical and Biological Engineering, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.ORCID 0000-0001-6497-9754
Pipsa SaharinenTranslational Cancer Medicine Program and Department of Biochemistry and Developmental Biology, University of Helsinki, Helsinki, Finland.ORCID 0000-0003-2652-0584
Jaap D van BuulDepartment of Medical Biochemistry at the Amsterdam UMC, location AMC, Amsterdam, The Netherlands.
Oliver FriedrichInstitute of Medical Biotechnology, Department of Chemical and Biological Engineering, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.ORCID 0000-0003-2238-2049
Richard S SmithJohn Innes Centre, Norwich Research Park, Norwich, UK.ORCID 0000-0001-9220-0787
Mateusz MajdaDepartment of Plant Molecular Biology, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-3405-2901
Taija MäkinenDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden. taija.makinen@igp.uu.se.ORCID 0000-0002-9338-1257
Funding
Knut and Alice Wallenberg FoundationUppsala University
Abstract
Lymphatic capillaries continuously take up interstitial fluid and adapt to resulting changes in vessel calibre
Indexed as
Cell ShapeCytoskeletonEndothelial CellsEndothelium, LymphaticActinsAnimalsAntigens, CDCadherin 5Cadherinscdc42 GTP-Binding ProteinHomeostasisHumansIntercellular JunctionsLymphatic VesselsMiceMicrotubulesActinsAntigens, CDCadherin 5Cadherinscdc42 GTP-Binding Protein
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.