Evidence map›Paper›PMID 40108969›Full record

ArticleArtificial organs2025

Ultrasound Assessment of Venous and Pulmonary Congestion in Left Ventricular Assist Devices Patients.

Attilio Iacovoni, Cinzia Giaccherini, Sara Paris, Raffaele Abete, Claudia Vittori, Riccardo Maria Inciardi, Ottavio Zucchetti, Amedeo Terzi, Michele Senni

Abstract read
In one paragraph

Article in Artificial organs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The rise of point-of-care ultrasound in cardiopulmonary diagnostics.European heart journal. Imaging methods and practice · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Attilio IacovoniCardiovascular Department, Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy.ORCID https://orcid.org/0000-0003-0347-6672
Cinzia GiaccheriniFROM Research Foundation E.T.S., Papa Giovanni XXIII Hospital, Bergamo, Italy.
Sara ParisInstitute of Cardiology, ASST Spedali Civili di Brescia, Brescia, Italy.
Raffaele AbeteCardiovascular Department, Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy.
Claudia VittoriCardiovascular Department, Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy.
Riccardo Maria InciardiInstitute of Cardiology, ASST Spedali Civili di Brescia, Brescia, Italy.
Ottavio ZucchettiCardiovascular Department, Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy.ORCID https://orcid.org/0000-0003-0564-7578
Amedeo TerziCardiovascular Department, Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy.
Michele SenniCardiovascular Department, Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA significant number of (left ventricular assist device) LVAD patients (pts) have hemodynamic-related adverse events requiring right heart catheterization (RHC). Venous and lung ultrasound is an established method for evaluating congestion in heart failure pts. This study aimed to investigate the role of these ultrasound parameters in the hemodynamic assessment of LVAD pts.

methodsRHC and complete echocardiography were performed on 50 consecutive LVAD pts, 12 of whom were the validation cohort. Pts were stratified based on right atrial pressure (RAP) ≥ 7 mmHg and pulmonary capillary wedge pressure (PCWP) > 15 mmHg.

resultsThe median LVAD follow-up time was 400 (209-900) days. Baseline characteristics were similar between high vs. normal RAP groups, except for NYHA class and renal function in the former group. High vs. normal PCWP showed a greater NYHA class and a furosemide dose. All hemodynamic parameters were significantly different in the high RAP group except for cardiac output (CO) and cardiac index (CI). In contrast, in the high PCWP group, no differences in CO, CI, and pulmonary vascular resistances were apparent. The most accurate non-invasive variable for detecting high RAP was renal venous stasis index (RVSI), receiver-operating characteristic curves for areas under the curve (AUC), 0.78 (95% CI, 0.62-0.93). Estimated left atrial pressure (LAP-eRAP) was the most accurate non-invasive value to discriminate high PCWP (AUC 0.85 95% CI 0.73-0.98).

conclusionThis study found a good correlation between RAP, PWCP, and non-invasive parameters, such as RVSI and LAP-eRAP, suggesting the importance of peripheral venous ultrasound in LVAD patients.

Indexed as

Heart-Assist DevicesHeart FailureLungPulmonary EdemaAdultAgedAtrial PressureCardiac CatheterizationEchocardiographyFemaleHemodynamicsHumansMaleMiddle AgedPulmonary Wedge PressureUltrasonographyDoppler vein signalsechocardiographyleft ventricular assisted devicePOCUS

Identifiers

PMID40108969
PMCPMC12179757

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.