ArticleCureus2025
The Possible Association Between Chronic Toxoplasmosis and Type-2 Diabetes Mellitus In Women: A Case-Control Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Association between type-2 diabetes and Toxoplasma gondii seropositivity: a systematic review and meta-analysis.Folia parasitologica · 2025Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe parasite
methodsA total of 274 samples were collected from women of reproductive age (18-55 years) as they were relevant for both chronic toxoplasmosis and T2DM. Serological testing was performed to detect the presence of
resultsAmong the participants, 46 (16.8%) were seropositive for chronic toxoplasmosis, and 68 (24.8%) were diagnosed with T2DM. Statistical analysis revealed that women with chronic toxoplasmosis were 2.3 times more likely to have T2DM compared to women without toxoplasmosis (OR = 2.289, CI: 1.171-4.473, p-value < 0.05). The study also found a significant association between education level and T2DM, with educated women being at lower risk of having T2DM (p-value < 0.05).
conclusionThis study highlights a statistically significant association between chronic toxoplasmosis and T2DM. Women who were seropositive for chronic toxoplasmosis were more likely to have T2DM compared to seronegative individuals. These findings contribute to the growing body of evidence suggesting a potential link between chronic infections and metabolic disorders. Further research is needed to establish causation, elucidate underlying mechanisms, and explore potential interventions to mitigate the risk of T2DM in individuals with chronic toxoplasmosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.