Evidence map›Paper›PMID 40110221›Full record

ArticleEuropean heart journal. Digital health2025

A comparison of artificial intelligence-enhanced electrocardiography approaches for the prediction of time to mortality using electrocardiogram images.

Arunashis Sau, Boroumand Zeidaabadi, Konstantinos Patlatzoglou, Libor Pastika, Antônio H Ribeiro, Ester Sabino, Nicholas S Peters, Antonio Luiz P Ribeiro, Daniel B Kramer, Jonathan W Waks and 1 more

Abstract read
In one paragraph

Article in European heart journal. Digital health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Reliability of Artificial Intelligence-enhanced Electrocardiography.medRxiv : the preprint server for health sciences · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Computational modelling of biological systems now and then: revisiting tools and visions from the beginning of the century.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Arunashis SauNational Heart and Lung Institute, Imperial College London, London, UK.ORCID https://orcid.org/0000-0002-0204-7078
Boroumand ZeidaabadiNational Heart and Lung Institute, Imperial College London, London, UK.
Konstantinos PatlatzoglouNational Heart and Lung Institute, Imperial College London, London, UK.
Libor PastikaNational Heart and Lung Institute, Imperial College London, London, UK.
Antônio H RibeiroDepartment of Information Technology, Uppsala University, Uppsala, Sweden.
Ester SabinoDepartment of Infectious Diseases, School of Medicine and Institute of Tropical Medicine, University of São Paulo, São Paulo, Brazil.
Nicholas S PetersNational Heart and Lung Institute, Imperial College London, London, UK.ORCID https://orcid.org/0000-0002-3581-8078
Antonio Luiz P RibeiroDepartment of Internal Medicine, Faculdade de Medicina, and Telehealth Centre and Cardiology Service, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Daniel B KramerNational Heart and Lung Institute, Imperial College London, London, UK.ORCID https://orcid.org/0000-0003-4241-3586
Jonathan W WaksHarvard-Thorndike Electrophysiology Institute, Beth Israel Deaconess Medical Centre, Harvard Medical School, Boston, MA, USA.
Fu Siong NgNational Heart and Lung Institute, Imperial College London, London, UK.ORCID https://orcid.org/0000-0002-8681-4368

Funding

Sao Paulo-Minas Gerais Tropical Medicine Research Center for Chagas Disease Biomarker DiscoveryU19AI098461 · NIAID · FUNDACAO FACULDADE DE MEDICINA · PI PEREIRA, ALEXANDRE DA COSTA · 2017 to 2021
$2.1M
"Sao Paulo-Minas Gerais Center for Chagas Disease Treatment (SaMiTrop)"U01AI168383 · NIAID · FUNDACAO FACULDADE DE MEDICINA · PI Ester Cerdeira Sabino · 2022 to 2026
$1.9M
NIAID NIH HHS U01 AI168383NIAID NIH HHS U19 AI098461
6 · The paper itself

Abstract

Aims: Most artificial intelligence-enhanced electrocardiogram (AI-ECG) models used to predict adverse events including death require that the ECGs be stored digitally. However, the majority of clinical facilities worldwide store ECGs as images. Methods and results: A total of 1 163 401 ECGs (189 539 patients) from a secondary care data set were available as both natively digital traces and PDF images. A digitization pipeline extracted signals from PDFs. Separate 1D convolutional neural network (CNN) models were trained on natively digital or digitized ECGs, with a discrete-time survival loss function to predict Conclusion: Both the image 2D CNN and digitized 1D CNN enable mortality prediction from ECG images, with comparable performance to natively digital 1D CNN. Models trained on natively digital 1D ECGs can also be applied to digitized 1D ECGs, without any significant loss in performance. This work allows AI-ECG mortality prediction to be applied in diverse global settings lacking digital ECG infrastructure.

Indexed as

artificial intelligenceECGmortalityrisk prediction

Identifiers

PMID40110221
PMCPMC11914724

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.