ArticleFrontiers in aging neuroscience2025
Cognitive outcomes after extracranial-intracranial bypass surgery in elderly patients diagnosed with atherosclerotic cerebral steno-occlusive artery disease.
Article in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Semi-Quantitative Assessment of Regional Cerebral Blood Flow Changes Following Extracranial-Intracranial Bypass Using SPECT: A Single-Center Retrospective Study.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The safety and clinical effectiveness of extracranial-intracranial (EC-IC) bypass surgery in elderly patients with atherosclerotic internal carotid artery and/or middle cerebral artery steno-occlusive (ACMSO) disease remain ambiguous. Here, we analyzed our experience of EC-IC bypass surgery to evaluate its clinical safety and effect on the cognitive function for elderly patients with ACMSO. Methods: This retrospective study enrolled patients >60 years of age diagnosed with ACMSO who underwent EC-IC bypass surgery at the authors' center between January 2018 and January 2021. Indications for bypass surgery included symptomatic ACMSO defined by cerebral angiography and evidence of relative hypoperfusion in the territories of steno-occlusive arteries based on computed tomography perfusion (CTP) neuroimaging. All patients underwent the Montreal Cognitive Assessment preoperatively and 2 years after bypass surgery. Clinical data, such as the National Institute of Health Stroke Scale and cognitive function scores, and CTP parameters were retrospectively analyzed. Results: The study cohort ultimately included data from 65 patients (60-68 years of age; median age, 66 years) who underwent 82 bypass surgeries. The patency rate of bridge arteries was 100% on intraoperative fluoroscopy and 95.0% (76/80) according to cerebral angiography at the last follow-up. The perioperative stroke rate was 1.54 % and the mortality rate was 3.08% in the 2nd year of follow-up. Compared with preoperative data, the mismatch volume of CTP was reduced ( Conclusion: EC-IC bypass surgery was safe and improved cognitive function in elderly patients diagnosed with ACMSO. Reversible cerebral perfusion function is one of the better prognoses, which needs to be confirmed in future study.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.