ArticleAnnals of medicine2025
Retinal and choroidal microvascular analysis by swept-source optical coherence tomography angiography in thyroid-associated ophthalmopathy (TAO) and hyperthyroidism without clinical signs of TAO.
Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Editorial: Imaging in the diagnosis and treatment of eye diseases.Frontiers in ophthalmology · 2026Article
- Effects of endoscopic transnasal orbital decompression on anterior segment ocular blood flow and clinical outcome in thyroid-associated ophthalmopathy: a retrospective study.American journal of translational research · 2026Article
- Retinal Microvascular and Orbital Structural Alterations in Thyroid Eye Disease.Journal of clinical medicine · 2026Article
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Authors and funding
10 authors.
Funding
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Abstract
objectiveTo analyse retinal and choroidal microvascular alterations in patients with thyroid-associated ophthalmopathy (TAO) and hyperthyroidism without signs of TAO using swept-source optical coherence tomography angiography (SS-OCTA) and to investigate the potential reasons for ocular microvascular changes in patients with TAO.
methodsThirty patients with active TAO (group A), thirty patients with hyperthyroidism without signs of TAO (group B), and thirty healthy subjects (group C) were recruited. The images of macula and optic nerve head were obtained by SS-OCTA. Vessel density (VD) of superficial capillary plexus (SCP), deep capillary plexus, radial peripapillary capillary and choriocapillaris (CC), choroidal vascularity index, foveal avascular zone area, macular thickness, macular ganglion cell complex thickness, choroidal thickness (CT), and retinal nerve fibre layer thickness were measured.
resultsGroup A had significantly higher VD of SCP than group C (all
conclusionWe noted a difference in the VD of SCP and CC between patients with TAO and patients with hyperthyroidism without signs of TAO. These relative differences in ocular microvasculature indicated that local (orbital) and systemic (thyroid-related) factors may both play a role in disease presentation and progression, with orbital factors having a greater impact.
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