Evidence map›Paper›PMID 40113872›Full record

ArticleScientific reports2025

Discovery of a human parvovirus B19 analog (Erythroparvovirus) in cats.

Gianvito Lanave, Francesco Pellegrini, Georgia Diakoudi, Cristiana Catella, Alessandra Cavalli, Paolo Capozza, Gabriella Elia, Barbara Di Martino, Eric Zini, Giuseppe Pollicino and 6 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Gianvito LanaveDepartment of Veterinary Medicine, University of Bari Aldo Moro, Valenzano, Bari, Italy. gianvito.lanave@uniba.it.
Francesco PellegriniDepartment of Veterinary Medicine, University of Bari Aldo Moro, Valenzano, Bari, Italy.
Georgia DiakoudiDepartment of Veterinary Medicine, University of Bari Aldo Moro, Valenzano, Bari, Italy.
Cristiana CatellaDepartment of Veterinary Medicine, University of Bari Aldo Moro, Valenzano, Bari, Italy.
Alessandra CavalliDepartment of Veterinary Medicine, University of Bari Aldo Moro, Valenzano, Bari, Italy.
Paolo CapozzaDepartment of Veterinary Medicine, University of Bari Aldo Moro, Valenzano, Bari, Italy.
Gabriella EliaDepartment of Veterinary Medicine, University of Bari Aldo Moro, Valenzano, Bari, Italy.
Barbara Di MartinoDepartment of Veterinary Medicine, University of Teramo, Teramo, Italy.
Eric ZiniAniCura Istituto Veterinario Novara, Granozzo Con Monticello, Novara, Italy.
Giuseppe PollicinoAniCura Istituto Veterinario Novara, Granozzo Con Monticello, Novara, Italy.
Andrea ZatelliDepartment of Veterinary Medicine, University of Bari Aldo Moro, Valenzano, Bari, Italy.
Krisztián BányaiDepartment of Pharmacology and Toxicology, University of Veterinary Medicine, Budapest, Hungary.
Antonio LavazzaExperimental Zooprophylactic Institute of Lombardia and Emilia Romagna, Brescia, Italy.
Nicola DecaroDepartment of Veterinary Medicine, University of Bari Aldo Moro, Valenzano, Bari, Italy.
Michele CameroDepartment of Veterinary Medicine, University of Bari Aldo Moro, Valenzano, Bari, Italy.
Vito MartellaDepartment of Veterinary Medicine, University of Bari Aldo Moro, Valenzano, Bari, Italy.

Funding

European Union NextGeneration EU-MUR PNRR Extended Partnership initiative on Emerging Infectious Diseases (Project no. PE00000007, INF-ACT)Ministero dell'Istruzione, dell'Università e della Ricerca PRIN 2022 "Investigating Hepatotropic Viruses in carnivores and humans in a One Health perspective" (HVOH) prot. 2022EPP2TTMinistero dell'Istruzione, dell'Università e della Ricerca PRIN 2022 PNRR "Exploring the virome of domestic dogs and cats COVDC (Comprehending virome of domestic carnivores): exploring the viral diversity of domestic carnivores and One Health implications prot. P2022FR49NNational Laboratory for Infectious Animal Diseases, Antimicrobial Resistance, Veterinary Public Health and Food Chain Safety RRF-2.3.1-21-2022-00001National Laboratory of Virology RRF-2.3.1-21-2022-00010
6 · The paper itself

Abstract

Two feral cats (from the same colony) were presented to the veterinary clinic for weakness, weight loss, and anorexia. The cats were part of a study on feline hepatotropic viruses (collection A, 43 animals). On metaviromic investigation, parvoviral reads were identified in the sera of the two cats. The feline parvovirus genome was 5.3 kb long with an organization similar to other members of the Erythroparvovirus genus. In the ORF1 (nonstructural proteins) and ORF2 (VP1/VP2 precursor) the feline virus displayed 43.1% and 49.1% nucleotide identity to human parvovirus B19, and 48.9% and 56.6% to chipmunk parvovirus. Sequence identity to canine/feline protoparvovirus (Protoparvovirus carnivoran 1) was as low as 36.5% % and 29.2% in the ORF1 and ORF2, respectively. Using a quantitative PCR assay, the virus was also identified in an additional ten cats (prevalence 27.6%, 12/43) from collection A and in 15/1150 (1.3%) of archival sera (collection B), revealing a higher infection rate in cats with altered hepatic markers, suggestive of hepatic distress. The findings of our study extend the list of known parvoviruses in the feline host.

Indexed as

Cat DiseasesParvoviridae InfectionsParvovirus B19, HumanAnimalsCatsGenome, ViralHumansOpen Reading FramesPhylogenyCatErythroparvovirusHepatitisSera

Identifiers

PMID40113872
PMCPMC11926167

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.