Evidence map›Paper›PMID 40114634›Full record

Trial reportThe Journal of manual & manipulative therapy2026

Effects of a two-week instrument-assisted soft tissue mobilization and exercise therapy versus sham and exercise on gait kinetics in moderate knee osteoarthritis: a randomized controlled trial.

Zahra Karimi Soloklo, Sahar Boozari, Sedighe Kahrizi

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of manual & manipulative therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zahra Karimi SolokloDepartment of Physiotherapy, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.ORCID 0009-0004-8165-9161
Sahar BoozariDepartment of Physiotherapy, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.ORCID 0000-0002-8014-1422
Sedighe KahriziDepartment of Physiotherapy, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.ORCID 0000-0001-7439-3474

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionKnee osteoarthritis (KOA) is a common joint disease that affects mobility and daily activities. Instrument-assisted soft tissue mobilization (IASTM) is widely used as a conservative treatment due to its potential effects on soft tissues. This study evaluates the effects of IASTM on pain, range of motion (ROM), health status, and gait kinetics in KOA patients.

methodsThirty individuals with unilateral KOA were randomized into two groups: IASTM with routine exercises and sham IASTM with exercises, over four sessions in two weeks. Pain, ROM, and WOMAC scores were assessed pre-treatment and 48 hours post-treatment. Gait kinetics, including vertical ground reaction force and knee adduction moment, were measured at three walking speeds (preferred, fixed, and fast) before and after treatment.

resultsMixed ANOVA revealed significant improvements in pain, ROM, and WOMAC scores in both groups. The IASTM group showed greater improvements in pain, knee flexion, ankle plantarflexion, and WOMAC pain scores, as indicated by a significant group*time interaction. For kinetics, the only significant finding was a longer time to heel strike transient in the IASTM group. At fast speed, most kinetic variables increased significantly in both groups.

conclusionBoth IASTM and sham interventions with exercise improved pain and ROM. However, the IASTM group experienced greater improvements. Additionally, IASTM led to a longer time to heel strike transient, suggesting improved shock absorption. Overall, IASTM may serve as a beneficial adjunctive intervention for alleviating symptoms in KOA patients and improving gait under challenging conditions, such as fast-speed walking.

Indexed as

Exercise TherapyGaitOsteoarthritis, KneeTherapy, Soft TissueAgedFemaleHumansMaleMiddle AgedPain MeasurementRange of Motion, ArticularTreatment OutcomebiomechanicsGraston techniqueKnee painsoft tissue releasewalking

Identifiers

PMID40114634
PMCPMC13061077

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.