Evidence mapPaperPMID 40114978Full record

ArticleBioinorganic chemistry and applications2025

An Innovative Approach Based on the Green Synthesis of Silver Nanoparticles Using Pomegranate Peel Extract for Antibacterial Purposes.

Rocío Díaz-Puertas, Francisco J Álvarez-Martínez, Enrique Rodríguez-Cañas, Fernando Borrás, Artur J M Valente, José A Paixao, Alberto Falcó, Ricardo Mallavia

Abstract read
In one paragraph

Article in Bioinorganic chemistry and applications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Green-synthesizedRSC advances · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rocío Díaz-PuertasInstitute of Research, Development and Innovation in Healthcare Biotechnology in Elche (IDiBE), Miguel Hernández University, Elche 03202, Alicante, Spain.ORCID https://orcid.org/0000-0002-3288-5697
Francisco J Álvarez-MartínezInstitute of Research, Development and Innovation in Healthcare Biotechnology in Elche (IDiBE), Miguel Hernández University, Elche 03202, Alicante, Spain.ORCID https://orcid.org/0000-0002-5275-1282
Enrique Rodríguez-CañasInstitute of Research, Development and Innovation in Healthcare Biotechnology in Elche (IDiBE), Miguel Hernández University, Elche 03202, Alicante, Spain.ORCID https://orcid.org/0000-0002-7102-9711
Fernando BorrásStatistics and Operative Research Department, Miguel Hernández University, Elche 03202, Alicante, Spain.ORCID https://orcid.org/0000-0002-5519-4573
Artur J M ValenteDepartment of Chemistry, University of Coimbra, Coimbra 3004-535, Portugal.ORCID https://orcid.org/0000-0002-4612-7686
José A PaixaoDepartment of Physics, University of Coimbra, Coimbra 3004-516, Portugal.ORCID https://orcid.org/0000-0003-4634-7395
Alberto FalcóFish Pathology Group, Institute of Aquaculture Torre de La Sal-Spanish National Research Council (IATS-CSIC), Cabanes 12595, Castellón, Spain.ORCID https://orcid.org/0000-0001-7726-6577
Ricardo MallaviaInstitute of Research, Development and Innovation in Healthcare Biotechnology in Elche (IDiBE), Miguel Hernández University, Elche 03202, Alicante, Spain.ORCID https://orcid.org/0000-0001-8058-1009

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study describes a green synthesis method for silver nanoparticles (AgNPs) using autochthonous "Mollar de Elche" pomegranate peel extract and optimized through a Python-programmed Box-Behnken design (BBD) created specifically for the work. The bioactive compounds in pomegranate, particularly punicalagin, serve as effective reducing and stabilizing agents. BBD was used to analyze the effects of dependent variables such as silver nitrate concentration, pomegranate extract concentration, and temperature on responses such as hydrodynamic diameter, polydispersity index, and zeta potential, minimizing experimental trials and highlighting variable interactions. Optimal conditions were experimentally validated and agreed well with the predicted values. The optimized AgNPs were characterized via ultraviolet-visible spectrophotometry, Fourier transform infrared spectroscopy, X-ray diffraction, and field emission scanning electron microscopy. These AgNPs demonstrated substantial antibacterial activity against

Indexed as

antibacterial activityBox–Behnkengreen synthesisPunica granatumresponse surface methodologysilver nanoparticles

Identifiers

PMID40114978
PMCPMC11925634

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.