Evidence map›Paper›PMID 40115732›Full record

ArticleJournal of equine science2025

Differences in serum iron concentrations between the summer and winter in Noma horses.

Keiichi Hisaeda, Tetsushi Ono, Takako Shimokawa-Miyama, Akihisa Hata, Eri Iwata, Yasuharu Hiasa, Emi Ohzawa, Teruaki Tozaki, Harutaka Murase, Masaki Takasu and 2 more

Abstract read
In one paragraph

Article in Journal of equine science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Keiichi HisaedaFaculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime 794-8555, Japan.
Tetsushi OnoFaculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime 794-8555, Japan.
Takako Shimokawa-MiyamaFaculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime 794-8555, Japan.
Akihisa HataFaculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime 794-8555, Japan.
Eri IwataFaculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime 794-8555, Japan.
Yasuharu HiasaHiasa Animal Clinic, 2-6-8 Koushouji, Imabari, Ehime 794-0805, Japan.
Emi OhzawaNoma Horse Preservation Society, 8 Nomakou, Imabari, Ehime 794-0082, Japan.
Teruaki TozakiLaboratory of Racing Chemistry, 1731-2 Tsuruta, Utsunomiya, Tochigi 320-0851, Japan.
Harutaka MuraseEquine Department, Japan Racing Association, 1-1-1 Nishi-Shimbashi, Minato-ku, Tokyo 105-0003, Japan.
Masaki TakasuGifu University Institute for Advanced Study, Gifu University, Gifu 501-1193, Japan.
Naohito NishiiJoint Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, Gifu 501-1193, Japan.
Hitoshi KitagawaFaculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime 794-8555, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We examined the differences in serum iron (Fe) concentrations and related variables between summer and winter in Noma horses. Blood samples were collected from 37 clinically normal horses seven consecutive times: September 2018, February 2019, October 2019, February 2020, September 2020, February 2021, and February 2022. Serum Fe concentrations ranged from 74 μg/dl to 316 μg/dl with a median of 176 μg/dl. The concentrations were lower in stallions compared with mares and geldings, tended to be low at 10-14 years of age, and then increased with age. Serum Fe concentrations were repeatedly low in summer and high in winter. Total iron-binding capacity (TIBC), Fe-saturation rate, hemoglobin (Hb), hematocrit (Ht), MCV, MCH, albumin, cholesterol, sodium (Na), potassium (K), chloride (Cl), and calcium (Ca) were lower in summer than in winter. However, creatinine, total protein, inorganic phosphorus, and Mg were higher in summer. The unsaturated iron-binding capacity, RBC count, blood urea nitrogen (BUN), glucose, and AST levels were not significantly different. Serum Fe concentrations were positively correlated with Hb, TIBC, Fe saturation rate, Ht, MCV, MCH, creatinine, albumin, glucose, cholesterol, AST, Na, Cl, and Ca, but negatively correlated with BUN and K. In Noma horses, serum Fe concentrations might be higher than the reference values for horses and consistently decrease in summer in parallel with Hb and MCV. The lowering of the serum Fe concentrations in summer may be due to a combination of the effects of Fe loss from sweating, dermatitis, insect bites, dietary composition, and/or unknown factors.

Indexed as

lowering in summerNoma horseseasonal changeserum iron concentration

Identifiers

PMID40115732
PMCPMC11919544

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.