ArticleFrontiers in endocrinology2025
Can weekend warriors and other leisure-time physical activity patterns reduce the atherogenic index of plasma (AIP)? A cross-sectional analysis based on NHANES 2007-2018.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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3 authors.
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Abstract
Background: With the shift in modern lifestyles, the relationship between physical activity (PA) and health has emerged as a significant concern in global public health. A sedentary lifestyle poses a substantial threat to cardiovascular health, particularly through the development of atherosclerosis, the primary pathological basis of cardiovascular disease (CVD) and a condition influenced by various lifestyle factors. The atherogenic index of plasma (AIP), a critical indicator for predicting cardiovascular disease risk, assesses an individual's risk of atherosclerosis by reflecting the ratio of high-density lipoprotein cholesterol (HDL-C) to triglycerides (TG). Despite the recognized importance of PA, the impact of various physical activity patterns on AIP remains unclear. Methods: This study utilized the National Health and Nutrition Examination Survey (NHANES) database from the United States. PA was assessed via a questionnaire, and participants were categorized into four groups: inactive, insufficiently active, weekend warriors (WW), and regularly active (RA). The AIP was calculated via the ratio of HDL-C to TG, with covariates such as age, sex, race, and body mass index controlled. Multivariate regression analysis served as the primary analytical method. Results: This study included a total of 24,504 participants. After adjusting for all potential covariates, RA (β=-0.044, Conclusion: RA is more effective in reducing AIP than WWs are. For inactive adults, engaging in more than 510 minutes of PA per week significantly reduces the AIP.
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