ReviewPhysiological research2025
Research Progress of Hydromorphone in Clinical Application.
Review in Physiological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07421674 (Application Research of Hydromorphinone Sustained-release Tablets in the Treatment of Elderly Patients With Cancer Pain Accompanied by Renal Insufficiency), which is not on this map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Application Research of Hydromorphinone Sustained-release Tablets in the Treatment of Elderly Patients With Cancer Pain Accompanied by Renal Insufficiency
Who cites it
9 citing papers in PubMed.
- Effects of Transverse Abdominis Plane Block with Ropivacaine-Hydromorphone versus. Ropivacaine in Cesarean Section: A Randomized Controlled Trial.Journal of pain research · 2026Trial
- Effects of hydromorphone-based patient-controlled intravenous analgesia on postpartum depression after cesarean section: a prospective randomized controlled trial.Frontiers in medicine · 2025Trial
- Sublingual Administration for Pain Control: Pharmacology, Clinical Applications and Future Directions.CNS drugs · 2026Review
- Molecular mechanism of hydromorphone preconditioning in cerebral ischemia/reperfusion‑induced inflammatory injury.International journal of molecular medicine · 2026Article
- Hydromorphone in Pediatric Pain Management: Pharmacology, Clinical Applications, and Safety Considerations-A Narrative Review.Healthcare (Basel, Switzerland) · 2026Review
- Differential effects of calcium channel blockers combined with various opioids on length of stay in hypertensive cardiac surgery patients: analysis of the MIMIC-IV database.BMC cardiovascular disorders · 2026Article
- The Role of Clinical Pharmacogenetics and Opioid Interactions in Pain Management: Current Evidence and Future Perspectives.Pharmaceutics · 2026Review
- Effect of Intrathecal Hydromorphone on the Duration and Efficacy of Postoperative Analgesia in Patients Undergoing Benign Anorectal Surgery: Protocol for a Randomized, Double-Blind, Controlled Trial.Journal of pain research · 2026Article
- From Peak to Plunge: A Multi-Database Analysis of State-Level Disparities in Hydromorphone Use in the US.Pharmacy (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A common opioid analgesic for cancer pain and, to a lesser extent, non-cancer pain, is hydromorphone (HM). Oral formulations as well as subcutaneous, intravenous, and other routes are frequently used for its administration. Its pharmacokinetics and pharmacodynamics have also been extensively researched. This article examines the pharmacological properties of hydromorphone and the development of its use both domestically and internationally with the goal of serving as a reference for the sensible clinical use of this medication. Key words Hydromorphone, Pharmacological action, Route of administration, Cancer pain, Adverse effects.
Indexed as
Identifiers
40116549PMC11995945What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.