Embedding a Choice Experiment in an Online Decision Aid or Tool: Scoping Review.

backgroundDecision aids empower patients to understand how treatment options match their preferences. Choice experiments, a method to clarify values used within decision aids, present patients with hypothetical scenarios to reveal their preferences for treatment characteristics. Given the rise in research embedding choice experiments in decision tools and the emergence of novel developments in embedding methodology, a scoping review is warranted.

objectiveThis scoping review examines how choice experiments are embedded into decision tools and how these tools are evaluated, to identify best practices.

methodsThis scoping review followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) guidelines. Searches were conducted on MEDLINE, PsycInfo, and Web of Science. The methodology, development and evaluation details of decision aids were extracted and summarized using narrative synthesis.

resultsOverall, 33 papers reporting 22 tools were included in the scoping review. These tools were developed for various health conditions, including musculoskeletal (7/22, 32%), oncological (8/22, 36%), and chronic conditions (7/22, 32%). Most decision tools (17/22, 77%) were developed in the United States, with the remaining tools originating in the Netherlands, United Kingdom, Canada, and Australia. The number of publications increased, with 73% (16/22) published since 2015, peaking at 4 publications in 2019. The primary purpose of these tools (20/22, 91%) was to help patients compare or choose treatments. Adaptive conjoint analysis was the most frequently used design type (10/22, 45%), followed by conjoint analysis and discrete choice experiments (DCEs; both 4/22, 18%), modified adaptive conjoint analysis (3/22, 14%), and adaptive best-worst conjoint analysis (1/22, 5%). The number of tasks varied depending on the design (6-12 for DCEs and adaptive conjoint vs 16-20 for conjoint analysis designs). Sawtooth software was commonly used (14/22, 64%) to embed choice tasks. Four proof-of-concept embedding methods were identified: scenario analysis, known preference phenotypes, Bayesian collaborative filtering, and penalized multinomial logit model. After completing the choice tasks patients received tailored information, 73% (16/22) of tools provided attribute importance scores, and 23% (5/22) presented a "best match" treatment ranking. To convey probabilistic attributes, most tools (13/22, 59%) used a combination of approaches, including percentages, natural frequencies, icon arrays, narratives, and videos. The tools were evaluated across diverse study designs (randomized controlled trials, mixed methods, and cohort studies), with sample sizes ranging from 23 to 743 participants. Over 40 different outcomes were included in the evaluations, with the decisional conflict scale being the most frequently used in 6 tools.

conclusionsThis scoping review provides an overview of how choice experiments are embedded into decision tools. It highlights the lack of established best practices for embedding methods, with only 4 proof-of-concept methods identified. Furthermore, the review reveals a lack of consensus on outcome measures, emphasizing the need for standardized outcome selection for future evaluations.