Evidence map›Paper›PMID 40118521›Full record

ArticleGenome research2025

De novo antibody identification in human blood from full-length single B cell transcriptomics and matching haplotype-resolved germline assemblies.

John Beaulaurier, Lynn Ly, J Andrew Duty, Carly Tyer, Christian Stevens, Chuan-Tien Hung, Akash Sookdeo, Alex W Drong, Shreyas Kowdle, Axel Guzman-Solis and 5 more

Abstract read
In one paragraph

Article in Genome research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

John Beaulaurier *Oxford Nanopore Technologies, Inc., New York, New York 10013, USA.ORCID 0000-0003-1536-888X
Lynn Ly *Oxford Nanopore Technologies, Inc., New York, New York 10013, USA.ORCID 0000-0001-6321-8996
J Andrew DutyIcahn School of Medicine at Mount Sinai, New York, New York 10029, USA.ORCID 0000-0003-3233-1181
Carly TyerOxford Nanopore Technologies, Inc., New York, New York 10013, USA.
Christian StevensIcahn School of Medicine at Mount Sinai, New York, New York 10029, USA.ORCID 0000-0003-2472-6984
Chuan-Tien HungIcahn School of Medicine at Mount Sinai, New York, New York 10029, USA.ORCID 0000-0001-6899-1312
Akash SookdeoOxford Nanopore Technologies, Inc., New York, New York 10013, USA.
Alex W DrongOxford Nanopore Technologies, Inc., New York, New York 10013, USA.ORCID 0000-0002-5209-6652
Shreyas KowdleIcahn School of Medicine at Mount Sinai, New York, New York 10029, USA.ORCID 0000-0002-7786-3547
Axel Guzman-SolisIcahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Domenico TortorellaIcahn School of Medicine at Mount Sinai, New York, New York 10029, USA.ORCID 0000-0003-0961-3535
Daniel J TurnerOxford Nanopore Technologies, Inc., New York, New York 10013, USA.
Sissel JuulOxford Nanopore Technologies, Inc., New York, New York 10013, USA.ORCID 0000-0002-0315-4449
Scott HickeyOxford Nanopore Technologies, Inc., New York, New York 10013, USA; benhur.lee@mssm.edu scott.hickey@nanoporetech.com.
Benhur LeeIcahn School of Medicine at Mount Sinai, New York, New York 10029, USA benhur.lee@mssm.edu scott.hickey@nanoporetech.com.ORCID 0000-0003-0760-1709

Funding

TRAINING PROGRAM: MECHANISMS OF VIRUS-HOST INTERACTIONST32AI007647 · NIAID · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI Domenico Tortorella · 2000 to 2026
$11.5M
Development of broadly neutralizing human monoclonal antibodies against henipavirusesR01AI185102 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Benhur Lee · 2025 to 2026
$1.6M
NIAID NIH HHS R01 AI185102NIAID NIH HHS T32 AI007647
6 · The paper itself

Abstract

Immunoglobulin (

Indexed as

AntibodiesB-LymphocytesHaplotypesTranscriptomeHumansImmunoglobulin Heavy ChainsSingle-Cell AnalysisAntibodiesImmunoglobulin Heavy Chains

Identifiers

PMID40118521
PMCPMC12047243

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.