Evidence map›Paper›PMID 40119211›Full record

ReviewArchives of pharmacal research2025

Covalent organic frameworks in cancer theranostics: advancing biomarker detection and tumor-targeted therapy.

Sonia Iranpour, Amir Abrishami, Amir Sh Saljooghi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of pharmacal research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sonia IranpourDepartment of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.
Amir AbrishamiDepartment of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.
Amir Sh SaljooghiDepartment of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran. Saljooghi@um.ac.ir.

Funding

Iran National Science Foundation 4015585
6 · The paper itself

Abstract

In recent years, covalent organic frameworks (COFs) have garnered considerable attention in the field of onco-nanotechnology as a new type of nanoporous construct due to their promising physicochemical properties, ease of modification, and ability to be coupled with several moieties and therapeutic molecules. They can not only be used as biocompatible nanocarriers to deliver therapeutic payloads to the tumor zone selectively but can also be combined with a variety of therapeutic modalities to achieve the desired treatments. This review comprehensively presented recent achievements and progress in COF-based cancer diagnosis, detection, and cancer therapy to provide a better prospect for further research. Herein our primary emphasis lies on exploring the application of COFs as potential sensors for cancer-derived biomarkers that have received comparatively less attention in previous discussions. While the utilization of COFs in solid tumor therapy has faced significant challenges in scientific research and clinical applications, we reviewed the most promising features that underscore their potential in cancer theranostics.

Indexed as

Antineoplastic AgentsBiomarkers, TumorMetal-Organic FrameworksNeoplasmsTheranostic NanomedicineAnimalsDrug Delivery SystemsHumansAntineoplastic AgentsBiomarkers, TumorMetal-Organic FrameworksBiomedical applicationsCancer managementCovalent organic frameworksOnco-nanotechnologyTheranostics

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.