Evidence map›Paper›PMID 40120341›Full record

ArticleUltrasonics sonochemistry2025

Non-porous silica nanoparticles as a cavitation sensitive vehicle for antibiotic delivery.

Grace Ball, Jack Stevenson, Faraz Amini Boroujeni, Ben Jacobson, Sarah A Kuehne, Margaret Lucas, Anthony Damien Walmsley, Paul Prentice, Zoe Pikramenou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ultrasonics sonochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Grace BallSchool of Chemistry, University of Birmingham, Edgbaston B15 2TT, UK.
Jack StevensonCentre for Medical & Industrial Ultrasonics, James Watt School of Engineering, University of Glasgow, Glasgow G12 8QQ, UK.
Faraz Amini BoroujeniCentre for Medical & Industrial Ultrasonics, James Watt School of Engineering, University of Glasgow, Glasgow G12 8QQ, UK.
Ben JacobsonCentre for Medical & Industrial Ultrasonics, James Watt School of Engineering, University of Glasgow, Glasgow G12 8QQ, UK.
Sarah A KuehneSchool of Science & Technology, Nottingham Trent University, Nottingham NG11 8NS, UK.
Margaret LucasCentre for Medical & Industrial Ultrasonics, James Watt School of Engineering, University of Glasgow, Glasgow G12 8QQ, UK.
Anthony Damien WalmsleySchool of Dentistry, College of Medical and Dental Sciences, University of Birmingham, Birmingham B5 7EG, UK.
Paul PrenticeCentre for Medical & Industrial Ultrasonics, James Watt School of Engineering, University of Glasgow, Glasgow G12 8QQ, UK.
Zoe PikramenouSchool of Chemistry, University of Birmingham, Edgbaston B15 2TT, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultrasound stimulated drug delivery is attractive for controlled dose and localised delivery to reduce excess loss of drug and side effects, which for antibiotics is pertinent to the fight against antimicrobial resistance. Low frequency ultrasound is commonly used in dental clinical practice for bacterial biofilm removal and is an attractive versatile stimulus for drug release. Here we introduce nonporous (amorphous) silica nanoparticles as a biocompatible, encapsulant for triggered drug release by low frequency ultrasound. A 20 kHz ultrasonic sonotrode is used in to evaluate the release of the antibiotic ciprofloxacin, CPX, from non-porous particles, CPX ⊂ SiO

Indexed as

Anti-Bacterial AgentsDrug CarriersDrug Delivery SystemsNanoparticlesSilicon DioxideCiprofloxacinDrug LiberationPorosityUltrasonic WavesAnti-Bacterial AgentsCiprofloxacinDrug CarriersSilicon DioxideCavitation responsiveControlled drug releaseSilica nanoparticlesUltrasound

Identifiers

PMID40120341
PMCPMC11981769

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.