Evidence map›Paper›PMID 40120950›Full record

ArticleJournal of affective disorders2025

From anxiety to depression: A longitudinal investigation into the role of anhedonia.

Amanda C Collins, Michael R Gallagher, Camryn Calafiore, D Gage Jordan, E Samuel Winer

Abstract read
In one paragraph

Article in Journal of affective disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amanda C CollinsDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, United States; Department of Psychiatry, Harvard Medical School, Boston, MA, United States; Center for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States. Electronic address: accollins@mgh.harvard.edu.
Michael R GallagherDepartment of Psychiatry and Behavioral Health, The Ohio State University Wexner Medical Center, Columbus, OH, United States; Department of Psychology, Mississippi State University, Mississippi State, MS, United States.
Camryn CalafioreDepartment of Psychology, The New School for Social Research, New York, NY, United States.
D Gage JordanDepartment of Psychiatry and Behavioral Health, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
E Samuel WinerDepartment of Psychology, The New School for Social Research, New York, NY, United States.

Funding

Training in the Science of Co-Occurring DisordersT32DA037202 · NIDA · DARTMOUTH COLLEGE · PI Lisa A. Marsch · 2014 to 2026
$4.7M
Reward Devaluation, Positive Valence Systems Disturbance, and ImpairmentR15MH101573 · NIMH · NEW SCHOOL UNIVERSITY · PI E. Samuel Winer · 2014 to 2026
$1.8M
NIDA NIH HHS T32 DA037202NIMH NIH HHS R15 MH101573
6 · The paper itself

Abstract

Anxiety and depression are highly comorbid with each other, warranting a need to better understand transdiagnostic mechanisms. Anhedonia has been hypothesized as a transdiagnostic mechanism but has often been investigated as a unidimensional factor. Thus, the current study examined how anticipatory and consummatory anhedonia, including how they interact with anxiety, predict next-week depression. Participants (N = 101) completed weekly assessments of anxiety, depression, and anhedonia. Using an iterative approach, we constructed four models to investigate independent and interactive effects of prior-week anxiety and anhedonia on next-week depression, as well as the effects of depression and anhedonia on anxiety. Our results indicate that anticipatory anhedonia is associated with next-week depression, and the association between anxiety and depression is greater when anticipatory anhedonia is high. The current findings provide insight into the transdiagnostic nature of anticipatory anhedonia between anxiety and depression. Future work should investigate how these associations may unfold over shorter time periods.

Indexed as

AnhedoniaAnxietyAnxiety DisordersDepressionAdolescentAdultAnticipation, PsychologicalFemaleHumansLongitudinal StudiesMaleMiddle AgedYoung AdultAnhedoniaAnxietyDepressionPositive valence systems

Identifiers

PMID40120950
PMCPMC12021549

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.