Evidence map›Paper›PMID 40121515›Full record

ArticleJournal of ovarian research2025

Effect of body mass index on pregnancy outcomes in young women with low-prognosis POSEIDON criteria after in vitro fertilization/intracytoplasmic sperm injection.

Yiting Ren, Chen Yang, Tian Tian, Rong Li, Lina Wang, Xiumei Zhen

Abstract read
In one paragraph

Article in Journal of ovarian research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yiting RenReproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Chen YangReproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Tian TianReproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Rong LiReproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Lina WangReproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Xiumei ZhenReproductive Medical Center, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China. xmzhen1970@aliyun.com.

Funding

National Key Research and Development Program of China 2022YFC2703800
6 · The paper itself

Abstract

backgroundThe aim of this study was to investeigate the pregnancy outcomes of young women with low prognosis according to the POSEIDON criteria after IVF/ICSI cycles and to explore the effect of body mass index (BMI) on pregnancy outcomes.

methodsThis was a retrospective cohort study conducted in women who underwent their first IVF/ICSI cycle treatment between January 2018 and December 2020, Among them, these patients who met criteria for POSEIDON group1and 3 were further categorized into four groups according to the China body mass index(BMI) classification, we analyzed the effect of BMI on pregnancy outcomes.

resultsA total of 29,354 patients were conducted first IVF/ICSI cycle between January 2018 and December 2020 in our reproductive center, 5981 women who met the criteria for POSEIDON 1 and POSEIDON 3 were further categorized into four groups according to the China body mass index(BMI) classification. There were not significant differences in the implantation rate and clinical pregnancy rate, regardless of fresh embryo transfer or frozen embryo transfer among the four groups (P > 0.05). The miscarriage rate of fresh embryo transfer was significantly higher in obese patients (P < 0.05), while the live birth rate of fresh embryo transfer and the cumulative live birth rate are significantly lower in obese patients(P < 0.05). BMI was a significant and independent predictor of the miscarriage rate of fresh embryo transfer (adjusted OR 1.111; 95% CI 1.042-1.184; p = 0.001) and the cumulative live-birth rate (adjusted OR 0.937; 95% CI 0.900-0.975; p = 0.001).

conclusionsOur study indicated that obesity negatively impacts the IVF/ICSI outcomes of young women with low prognosis, including higher miscarriage rate and lower live birth-rate and cumulative live-birth rate. In our study, we found that BMI was the best independent predictor of the miscarriage rate of fresh embryo transfer and cumulative live-birth rate of low-prognosis patients under 35 years old. Thus the best way to reduce these complications for young patients with a poor prognosis was to keep their BMI between 18.5 kg/m

Indexed as

Body Mass IndexFertilization in VitroSperm Injections, IntracytoplasmicAdultEmbryo TransferFemaleHumansObesityPregnancyPregnancy OutcomePregnancy RatePrognosisRetrospective StudiesBody Mass IndexIn Vitro Fertilization/IntraCytoplasmic Sperm InjectionPOSEIDON criteriaPregnancy Outcomes

Identifiers

PMID40121515
PMCPMC11929203

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.