Trial reportExperimental physiology2026
Effect of artificial gravity on calcaneal bone marrow adipose tissue and mineral content in female and male participants in 60 days of bed rest.
Trial report in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Modulation of bone marrow adipose tissue (BMAT) with prolonged inactivity was reported in haemopoietic but not in non-haemopoietic bones. This prospective randomized controlled trial submitted 16 men and 8 women to 60 days of 6° head-down-tilt bed rest. They were assigned to control, continuous or intermittent artificial gravity (AG) interventions. The AG consisted of daily centrifugation at 2g for 30 min. The serial foot pain questionnaire, MRI and dual-energy X-ray absorptiometry of the calcaneus were performed at baseline, during bed rest and at reambulation. At baseline, all groups had comparable calcaneal BMAT (P = 0.581) and bone mineral density (BMD) (P = 0.574). After bed rest, 83% of participants reported foot pain. Calcaneal BMAT was not significantly modulated after 60 days of bed rest (control, +0.2% ± 0.8%; continuous AG, +0.5% ± 1.1%; and intermittent AG, +0.1% ± 1.5%; P = 0.368). Calcaneal BMD was reduced at reambulation days 3 and 11 after 60 days of bed rest (-0.05 ± 0.06 and -0.06 ± 0.12 g/cm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.