Evidence map›Paper›PMID 40122880›Full record

ArticleTropical medicine and health2025

Time to consider doxycycline in the standard treatment of lymphatic filariasis? Emerging evidence on use of doxycycline as an adjunct to hygiene protocols.

Mian Zahid Jan Kakakhel, Shree Rath, Maheen Sheraz, Diya Rathi, Raheel Ahmed

Abstract readLetter
In one paragraph

Article in Tropical medicine and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mian Zahid Jan KakakhelRehman Medical College, Peshawar, Khyber Pakhtunkhwa, Pakistan. mianzahidjan3@gmail.com.
Shree RathAll India Institute of Medical Sciences, Bhubaneswar, India.
Maheen SherazContinental Medical College, Lahore, Pakistan.
Diya RathiDow University of Health Sciences, Karachi, Pakistan.
Raheel AhmedNational Heart and Lung Institute, Imperial College London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With lymphatic filariasis being a rampant condition in tropical countries, multiple treatment modalities are being explored for their efficacy and practicability of use in low resource settings. Doxycycline, a commonly available drug across the world, has been proposed to improve patient status in those suffering with lymphatic filariasis. In conjunct with hygiene protocols, emerging trials have highlighted the success of doxycycline as an add-on drug. In this letter, we highlight the major findings in recent trials, and the scope of integrating doxycycline into national elimination strategies against filariasis.

Indexed as

DoxycyclineHygiene protocolsLymphatic filariasis

Identifiers

PMID40122880
PMCPMC11931818

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.