ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2025
The association between sleep fragmentation and incident atrial fibrillation: a prospective cohort study in a community population.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Sleep disturbances after an ultra-trail endurance race: a field study.Sleep medicine: X · 2026Article
- Influence of sleep architectural disruptions on the evolution of atrial fibrillation.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
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Authors and funding
4 authors.
Funding
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Abstract
STUDY
objectivesSleep fragmentation (SF) has been recognized as a risk factor for cardiovascular disease. This study aims to investigate the impact of SF on atrial fibrillation (AF).
methodsA total of 2,377 participants without pre-existing AF from the Sleep Heart Health Study were enrolled in this study. Wake after sleep onset (WASO), SF index, arousal index, and sleep efficiency were used to describe SF objectively. Multivariate logistic regression and restricted cubic spline analysis were conducted to investigate the association between SF and AF.
resultsDuring a mean follow-up of 5.3 years, we observed 221 (9.30%) participants developed AF. Participants with incident AF had significantly worse WASO, arousal index, and sleep efficiency compared with those without incident AF. Multivariate logistic regression revealed that WASO was associated with incident AF in both overall sample and participants without obstructive sleep apnea, with odds ratios of 1.61 (95% confidence interval: 1.04, 2.49;
conclusionsThis study demonstrated that worsening SF, as assessed by WASO, sleep efficiency, and arousal index, was associated with an increased odds of incident AF in participants without obstructive sleep apnea. Thus, improving SF may contribute to decreasing the odds of incident AF. CITATION: Wang L, Hui X, Huang R, Xiao Y. The association between sleep fragmentation and incident atrial fibrillation: a prospective cohort study in a community population.
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