ReviewFrontiers in nutrition2025
Metabolic disorder of nutrients-an emerging field in the pathogenesis of preeclampsia.
Review in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Altered AADAC Modulates Trophoblast Invasion and Suggests a Potential Angiogenic Regulatory Role in Severe Preeclampsia.International journal of molecular sciences · 2026Article
- Mediterranean Diet and Oxidative Balance During Pregnancy: Molecular Insights into Mitigating the Impact of Environmental Pollution.Current issues in molecular biology · 2026Review
- The Mediating Role of Blood Metabolites in the Association between Basal Metabolic Rate and Obstetrical Disorders: A Mendelian Randomization AnalysisEndocrine, metabolic & immune disorders drug targets · 2026Article
- Oxidative Stress-Related Metabolomic Alterations in Pregnancy: Evidence from Exposure to Air Pollution, Metals/Metalloid, and Tobacco Smoke.Antioxidants (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is well acknowledged that metabolic disorder binds closely with preeclampsia, though some of the causal relationships are still ambiguous. This review systematically summarizes the metabolic characteristics of carbohydrates, lipids, amino acids, and glycans in preeclampsia, highlighting their roles in oxidative stress, trophoblast autophagy, inflammatory response, and vascular tone regulation. Key findings include upregulated glycolysis and impaired mitochondrial function contributing to ATP deficiency, dysregulated lipid metabolism exacerbating oxidative stress and vascular dysfunction, and amino acid imbalances disrupting immune responses and redox homeostasis. Emerging therapies, such as metformin and pravastatin, demonstrate potential in targeting these pathways for prevention and treatment. Here, we reviewed thoroughly the related literature with a view to delineating the potential association of nutrient metabolism with preeclampsia, so that we could explore a promising therapeutic approach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.